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Acnat2 acyl-coenzyme A amino acid N-acyltransferase 2 [ Mus musculus (house mouse) ]

Gene ID: 209186, updated on 2-Nov-2024

Summary

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Official Symbol
Acnat2provided by MGI
Official Full Name
acyl-coenzyme A amino acid N-acyltransferase 2provided by MGI
Primary source
MGI:MGI:2444345
See related
Ensembl:ENSMUSG00000060317 AllianceGenome:MGI:2444345
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C730036D15Rik
Summary
Predicted to enable N-acyltransferase activity and fatty acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid metabolic process. Predicted to be active in peroxisome. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in liver adult (RPKM 17.2), kidney adult (RPKM 14.0) and 1 other tissue See more
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Genomic context

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See Acnat2 in Genome Data Viewer
Location:
4 B1; 4 26.37 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (49374458..49408151, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (49374458..49408151, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene phospholipid phosphatase related 1 Neighboring gene predicted gene, 22685 Neighboring gene tumor suppressor candidate 2 pseudogene Neighboring gene recombination signal binding protein for immunoglobulin kappa J region, pseudogene 1 Neighboring gene predicted gene 12451 Neighboring gene predicted gene 12452 Neighboring gene recombination signal binding protein for immunoglobulin kappa J region, pseudogene 2 Neighboring gene acyl-coenzyme A amino acid N-acyltransferase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Novel functions of acyl-CoA thioesterases and acyltransferases as auxiliary enzymes in peroxisomal lipid metabolism. Hunt MC, et al. Prog Lipid Res, 2008 Nov. PMID 18538142
  2. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables N-acyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables fatty acyl-CoA hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables thiolester hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in acyl-CoA metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in acyl-CoA metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in fatty acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in fatty acid metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in peroxisome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in peroxisome ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
acyl-coenzyme A amino acid N-acyltransferase 2
Names
acyl-CoA:amino acid N-acyltransferase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001356289.1 → NP_001343218.1  acyl-coenzyme A amino acid N-acyltransferase 2

    Status: VALIDATED

    Source sequence(s)
    AK050308, AK050357, BX537352
    Consensus CDS
    CCDS18171.1
    UniProtKB/Swiss-Prot
    B2D099, Q8BGG9, Q91XC7
    Related
    ENSMUSP00000103326.2, ENSMUST00000107698.8
    Conserved Domains (2) summary
    pfam04775
    Location:15 → 139
    Bile_Hydr_Trans; Acyl-CoA thioester hydrolase/BAAT N-terminal region
    pfam08840
    Location:206 → 415
    BAAT_C; BAAT / Acyl-CoA thioester hydrolase C terminal

  2. NM_145368.3 → NP_663343.2  acyl-coenzyme A amino acid N-acyltransferase 2

    See identical proteins and their annotated locations for NP_663343.2

    Status: VALIDATED

    Source sequence(s)
    AK050308, BX537352
    Consensus CDS
    CCDS18171.1
    UniProtKB/Swiss-Prot
    B2D099, Q8BGG9, Q91XC7
    Related
    ENSMUSP00000080256.3, ENSMUST00000081541.9
    Conserved Domains (2) summary
    pfam04775
    Location:15 → 139
    Bile_Hydr_Trans; Acyl-CoA thioester hydrolase/BAAT N-terminal region
    pfam08840
    Location:206 → 415
    BAAT_C; BAAT / Acyl-CoA thioester hydrolase C terminal

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    49374458..49408151 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011249969.4 → XP_011248271.1  acyl-coenzyme A amino acid N-acyltransferase 2 isoform X1

    See identical proteins and their annotated locations for XP_011248271.1

    Conserved Domains (2) summary
    pfam04775
    Location:15 → 140
    Bile_Hydr_Trans; Acyl-CoA thioester hydrolase/BAAT N-terminal region
    cl21494
    Location:206 → 250
    Abhydrolase; alpha/beta hydrolases

  2. XM_036163935.1 → XP_036019828.1  acyl-coenzyme A amino acid N-acyltransferase 2 isoform X1

    Conserved Domains (2) summary
    pfam04775
    Location:15 → 140
    Bile_Hydr_Trans; Acyl-CoA thioester hydrolase/BAAT N-terminal region
    cl21494
    Location:206 → 250
    Abhydrolase; alpha/beta hydrolases
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BGG9.1 GenPept UniProtKB/Swiss-Prot:Q8BGG9

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