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Dip2c disco interacting protein 2 homolog C [ Mus musculus (house mouse) ]

Gene ID: 208440, updated on 2-Nov-2024

Summary

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Official Symbol
Dip2cprovided by MGI
Official Full Name
disco interacting protein 2 homolog Cprovided by MGI
Primary source
MGI:MGI:1920179
See related
Ensembl:ENSMUSG00000048264 AllianceGenome:MGI:1920179
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA0934; 9630044M06; 2900024P20Rik
Summary
Is expressed in cerebral cortex. Orthologous to human DIP2C (disco interacting protein 2 homolog C). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in CNS E18 (RPKM 8.8), whole brain E14.5 (RPKM 7.1) and 25 other tissues See more
Orthologs
human all
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Genomic context

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See Dip2c in Genome Data Viewer
Location:
13 A1; 13 3.7 cM
Exon count:
38
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (9326530..9718964)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (9276507..9668928)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_33614 Neighboring gene STARR-seq mESC enhancer starr_33615 Neighboring gene predicted gene 8784 Neighboring gene STARR-seq mESC enhancer starr_33616 Neighboring gene predicted gene, 46391 Neighboring gene eukaryotic translation initiation factor 4E nuclear import factor 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_33619 Neighboring gene STARR-seq mESC enhancer starr_33622 Neighboring gene STARR-seq mESC enhancer starr_33624 Neighboring gene STARR-seq mESC enhancer starr_33625 Neighboring gene predicted gene, 36423 Neighboring gene zinc finger, MYND domain containing 11 Neighboring gene STARR-positive B cell enhancer ABC_E4050 Neighboring gene STARR-positive B cell enhancer ABC_E1454 Neighboring gene predicted gene, 40665

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Brain transcriptome study through CRISPR/Cas9 mediated mouse Dip2c gene knock-out. Oo ZM, et al. Gene, 2020 Oct 20. PMID 32707302
  2. Autism candidate gene DIP2A regulates spine morphogenesis via acetylation of cortactin. Ma J, et al. PLoS Biol, 2019 Oct. PMID 31600191, Free PMC Article
  3. Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2004 Jun 30. PMID 15368895
  4. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
  5. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (4)  1 citation
  • Targeted (1) 

General gene information

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Markers

Homology

Clone Names

  • KIAA0934

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
disco-interacting protein 2 homolog C
Names
DIP2 disco-interacting protein 2 homolog C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081426.2 → NP_001074895.2  disco-interacting protein 2 homolog C

    See identical proteins and their annotated locations for NP_001074895.2

    Status: VALIDATED

    Source sequence(s)
    AC124579, AC131743, AC133934
    Consensus CDS
    CCDS36589.2
    UniProtKB/TrEMBL
    B2RQ71, E9PWR4
    Related
    ENSMUSP00000133806.2, ENSMUST00000174552.8
    Conserved Domains (2) summary
    cd05905
    Location:988 → 1552
    Dip2; Disco-interacting protein 2 (Dip2)
    pfam06464
    Location:8 → 118
    DMAP_binding; DMAP1-binding Domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    9326530..9718964
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006516475.5 → XP_006516538.1  disco-interacting protein 2 homolog C isoform X3

    UniProtKB/TrEMBL
    E9PWR4
    Conserved Domains (2) summary
    cd05905
    Location:992 → 1556
    Dip2; Disco-interacting protein 2 (Dip2)
    pfam06464
    Location:8 → 118
    DMAP_binding; DMAP1-binding Domain

  2. XM_006516473.3 → XP_006516536.1  disco-interacting protein 2 homolog C isoform X1

    UniProtKB/TrEMBL
    E9PWR4
    Conserved Domains (2) summary
    cd05905
    Location:1048 → 1612
    Dip2; Disco-interacting protein 2 (Dip2)
    pfam06464
    Location:8 → 174
    DMAP_binding; DMAP1-binding Domain

  3. XM_006516474.4 → XP_006516537.1  disco-interacting protein 2 homolog C isoform X2

    UniProtKB/TrEMBL
    E9PWR4
    Related
    ENSMUSP00000131238.3, ENSMUST00000169960.10
    Conserved Domains (2) summary
    cd05905
    Location:1044 → 1608
    Dip2; Disco-interacting protein 2 (Dip2)
    pfam06464
    Location:8 → 174
    DMAP_binding; DMAP1-binding Domain

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_172459.1: Suppressed sequence

    Description
    NM_172459.1: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.
Nucleotide Protein Strain
Heading Accession and Version

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