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Fmr1nb Fmr1 neighbor [ Mus musculus (house mouse) ]

Gene ID: 207854, updated on 2-Nov-2024

Summary

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Official Symbol
Fmr1nbprovided by MGI
Official Full Name
Fmr1 neighborprovided by MGI
Primary source
MGI:MGI:2672032
See related
Ensembl:ENSMUSG00000062170 AllianceGenome:MGI:2672032
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
NYSAR35; NY-SAR-35; 3830422N12Rik
Summary
Predicted to be located in membrane. Is expressed in reproductive system. Orthologous to human FMR1NB (FMR1 neighbor). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward placenta adult (RPKM 77.3) See more
Orthologs
human all
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Genomic context

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See Fmr1nb in Genome Data Viewer
Location:
X A7.1; X 34.86 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (67805460..67848167)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (68761839..68804561)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene FMRP translational regulator 1, opposite strand Neighboring gene fragile X messenger ribonucleoprotein 1 Neighboring gene STARR-seq mESC enhancer starr_47302 Neighboring gene serine/threonine/tyrosine interacting protein, pseudogene Neighboring gene predicted gene 6812

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Reverse genetics reveals single gene of every candidate on Hybrid sterility, X Chromosome QTL 2 (Hstx2) are dispensable for spermatogenesis. Morimoto K, et al. Sci Rep, 2020 Jun 3. PMID 32493902, Free PMC Article
  2. Immunomic analysis of human sarcoma. Lee SY, et al. Proc Natl Acad Sci U S A, 2003 Mar 4. PMID 12601173, Free PMC Article
  3. Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice. Miyata H, et al. Proc Natl Acad Sci U S A, 2016 Jul 12. PMID 27357688, Free PMC Article
  4. A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies. Breslow DK, et al. Nat Genet, 2018 Mar. PMID 29459677, Free PMC Article
  5. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC117577

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
fmr1 neighbor protein
Names
protein mNY-SAR-35

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001166619.2 → NP_001160091.1  fmr1 neighbor protein isoform 2

    See identical proteins and their annotated locations for NP_001160091.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate exon in the 5' coding region, compared to variant 1. The resulting protein (isoform 2) is shorter when it is compared to isoform 1.
    Source sequence(s)
    AC055766
    Consensus CDS
    CCDS53084.1
    UniProtKB/Swiss-Prot
    B2RQU9, Q4KL61, Q80ZA7, Q8BPD4
    Related
    ENSMUSP00000064543.6, ENSMUST00000069731.12

  2. NM_001166620.2 → NP_001160092.1  fmr1 neighbor protein isoform 3

    See identical proteins and their annotated locations for NP_001160092.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks two alternate exons, compared to variant 1. The resulting protein (isoform 3) is shorter when it is compared to isoform 1.
    Source sequence(s)
    AC055766
    Consensus CDS
    CCDS53085.1
    UniProtKB/TrEMBL
    B7ZW84
    Related
    ENSMUSP00000110294.2, ENSMUST00000114647.8

  3. NM_174993.3 → NP_778158.2  fmr1 neighbor protein isoform 1

    See identical proteins and their annotated locations for NP_778158.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and it encodes the longest protein (isoform 1).
    Source sequence(s)
    AC055766
    Consensus CDS
    CCDS30172.1
    UniProtKB/Swiss-Prot
    B2RQU9, Q4KL61, Q80ZA7, Q8BPD4
    UniProtKB/TrEMBL
    B7ZNB2, B7ZWA0
    Related
    ENSMUSP00000071748.7, ENSMUST00000071848.7

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    67805460..67848167
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q80ZA7.1 GenPept UniProtKB/Swiss-Prot:Q80ZA7

Gene LinkOut

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