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BC034090 cDNA sequence BC034090 [ Mus musculus (house mouse) ]

Gene ID: 207792, updated on 2-Nov-2024

Summary

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Official Symbol
BC034090provided by MGI
Official Full Name
cDNA sequence BC034090provided by MGI
Primary source
MGI:MGI:2672904
See related
Ensembl:ENSMUSG00000033722 AllianceGenome:MGI:2672904
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA1614; 6820428L09
Summary
Predicted to be involved in centrosome cycle; establishment or maintenance of cell polarity; and regulation of cellular localization. Predicted to be active in apical plasma membrane; cell cortex; and nucleus. Orthologous to human KIAA1614 (KIAA1614). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in kidney adult (RPKM 13.3), adrenal adult (RPKM 6.5) and 19 other tissues See more
Orthologs
human all
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Genomic context

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See BC034090 in Genome Data Viewer
Location:
1 G3; 1 66.47 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (155088217..155123504, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (155212471..155245639, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 30922 Neighboring gene STARR-positive B cell enhancer ABC_E2569 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:157001032-157001362 Neighboring gene STARR-positive B cell enhancer ABC_E500 Neighboring gene major histocompatibility complex, class I-related Neighboring gene syntaxin 6 Neighboring gene high mobility group protein B3 pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:157081058-157081259 Neighboring gene predicted gene, 31102 Neighboring gene STARR-positive B cell enhancer ABC_E7760 Neighboring gene xenotropic and polytropic retrovirus receptor 1 Neighboring gene predicted gene, 17974 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:157242079-157242280 Neighboring gene STARR-positive B cell enhancer mm9_chr1:157264431-157264732 Neighboring gene STARR-seq mESC enhancer starr_02724 Neighboring gene predicted gene, 31713

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2003 Aug 31. PMID 14621295
  2. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in centrosome cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in establishment or maintenance of cell polarity IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of cellular localization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in apical plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cell cortex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein KIAA1614 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001370865.1 → NP_001357794.1  uncharacterized protein KIAA1614 homolog

    Status: VALIDATED

    Source sequence(s)
    AC110268
    Consensus CDS
    CCDS87895.1
    UniProtKB/TrEMBL
    A0A087WP46
    Related
    ENSMUSP00000139623.2, ENSMUST00000186156.7
    Conserved Domains (2) summary
    cd00992
    Location:1114 → 1195
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15737
    Location:337 → 461
    DUF4685; Domain of unknown function (DUF4685)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    155088217..155123504 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006530031.5 → XP_006530094.1  uncharacterized protein KIAA1614 homolog isoform X2

    Conserved Domains (2) summary
    cd00992
    Location:1046 → 1127
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15737
    Location:337 → 461
    DUF4685; Domain of unknown function (DUF4685)

  2. XM_148974.13 → XP_148974.3  uncharacterized protein KIAA1614 homolog isoform X1

    Conserved Domains (2) summary
    cd00992
    Location:1083 → 1164
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15737
    Location:306 → 430
    DUF4685; Domain of unknown function (DUF4685)

  3. XM_030252447.1 → XP_030108307.1  uncharacterized protein KIAA1614 homolog isoform X3

    UniProtKB/TrEMBL
    F6T2X5, Q8K058
    Related
    ENSMUSP00000037456.5, ENSMUST00000035914.5
    Conserved Domains (2) summary
    cd00992
    Location:752 → 833
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15737
    Location:1 → 99
    DUF4685; Domain of unknown function (DUF4685)

  4. XM_006530035.4 → XP_006530098.1  uncharacterized protein KIAA1614 homolog isoform X3

    UniProtKB/TrEMBL
    F6T2X5, Q8K058
    Conserved Domains (2) summary
    cd00992
    Location:752 → 833
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15737
    Location:1 → 99
    DUF4685; Domain of unknown function (DUF4685)

  5. XM_036163040.1 → XP_036018933.1  uncharacterized protein KIAA1614 homolog isoform X3

    UniProtKB/TrEMBL
    F6T2X5, Q8K058
    Conserved Domains (2) summary
    cd00992
    Location:752 → 833
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15737
    Location:1 → 99
    DUF4685; Domain of unknown function (DUF4685)

  6. XM_006530036.5 → XP_006530099.1  uncharacterized protein KIAA1614 homolog isoform X4

    UniProtKB/TrEMBL
    Q8K058
    Conserved Domains (2) summary
    cd00992
    Location:687 → 768
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15737
    Location:1 → 34
    DUF4685; Domain of unknown function (DUF4685)

  7. XM_036163046.1 → XP_036018939.1  uncharacterized protein KIAA1614 homolog isoform X5

    UniProtKB/TrEMBL
    Q8K058
    Conserved Domains (2) summary
    cd00992
    Location:619 → 700
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15737
    Location:1 → 34
    DUF4685; Domain of unknown function (DUF4685)

RNA

  1. XR_003954294.2 RNA Sequence

  2. XR_004941304.1 RNA Sequence

  3. XR_004941302.1 RNA Sequence

  4. XR_004941303.1 RNA Sequence

  5. XR_387502.5 RNA Sequence

  6. XR_878643.4 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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