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mt:ATPase8 mitochondrial ATPase subunit 8 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 19893538, updated on 18-Sep-2024

Summary

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Official Symbol
mt:ATPase8provided by FlyBase
Official Full Name
mitochondrial ATPase subunit 8provided by FlyBase
Primary source
FLYBASE:FBgn0013673
Locus tag
Dmel_CG34072
See related
AllianceGenome:FB:FBgn0013673
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
mt:ATPase8; ATP8
Summary
Predicted to enable proton transmembrane transporter activity. Predicted to be involved in ATP synthesis coupled proton transport. Predicted to be part of mitochondrial proton-transporting ATP synthase complex, coupling factor F(o). Is expressed in adult head. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See mt:ATPase8 in Genome Data Viewer
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) MT (non-nuclear) NC_024511.2 (3907..4068)

Chromosome MT - NC_024511.2Genomic Context describing neighboring genes Neighboring gene mitochondrial transfer RNA:Lysine-CTT Neighboring gene mitochondrial transfer RNA:Aspartic acid-GTC Neighboring gene mitochondrial ATPase subunit 6 Neighboring gene mitochondrial Cytochrome c oxidase subunit III Neighboring gene mitochondrial transfer RNA:Glycine-TCC

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_024511.2 Chromosome MT Reference Release 6 plus ISO1 MT non-nuclear

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Variation in mitochondrial genotype has substantial lifespan effects which may be modulated by nuclear background. Clancy DJ. Aging Cell, 2008 Dec. PMID 18727704
  2. Linkage disequilibria between mtDNA haplotypes and chromosomal arrangements in a natural population of Drosophila subobscura. Oliver P, et al. Heredity (Edinb), 2002 Aug. PMID 12136416
  3. RNase H1 promotes replication fork progression through oppositely transcribed regions of Drosophila mitochondrial DNA. González de Cózar JM, et al. J Biol Chem, 2019 Mar 22. PMID 30635398, Free PMC Article
  4. Coevolution of Drosophila melanogaster mtDNA and Wolbachia genotypes. Ilinsky Y. PLoS One, 2013. PMID 23349865, Free PMC Article
  5. Expression profiling of Drosophila mitochondrial genes via deep mRNA sequencing. Torres TT, et al. Nucleic Acids Res, 2009 Dec. PMID 19843606, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables proton transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in proton motive force-driven ATP synthesis IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ATP synthase F0 subunit 8

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_024511.2 Reference assembly

    Range
    3907..4068
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_009047269.1 Peptide Sequence

    See identical proteins and their annotated locations for YP_009047269.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    B2L9S1, B6E0P5, P84345
    UniProtKB/TrEMBL
    C7DZL0
    Related
    FBpp0100178
    Conserved Domains (1) summary
    pfam00895
    Location:1 → 53
    ATP-synt_8; ATP synthase protein 8
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P84345.1 P84345

Gene LinkOut

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