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CG31381 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 192528, updated on 28-Oct-2024

Summary

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Official Symbol
CG31381provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0043799
Locus tag
Dmel_CG31381
See related
AllianceGenome:FB:FBgn0043799
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BEST:LD10347; Dmel\CG31381
Summary
Predicted to enable tRNA dimethylallyltransferase activity. Predicted to be involved in tRNA modification. Predicted to be active in mitochondrion. Is expressed in several structures, including Malpighian tubule primordium; clypeo-labral primordium; embryonic anal pad; embryonic/larval midgut primordium; and gut section. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 35. Orthologous to human TRIT1 (tRNA isopentenyltransferase 1). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
all
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Genomic context

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See CG31381 in Genome Data Viewer
Location:
96B2-96B2; 3-86 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (24877045..24878827)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20702767..20704549)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Cyclin B3 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of the Drosophila atlastin interactome reveals VCP as a functionally related interactor. O'Sullivan NC, et al. J Genet Genomics, 2013 Jun 20. PMID 23790629
  2. Wolbachia and Virus Alter the Host Transcriptome at the Interface of Nucleotide Metabolism Pathways. Lindsey ARI, et al. mBio, 2021 Feb 9. PMID 33563832, Free PMC Article
  3. Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome. MacMillan HA, et al. Sci Rep, 2016 Jun 30. PMID 27357258, Free PMC Article
  4. The genetic basis for variation in olfactory behavior in Drosophila melanogaster. Arya GH, et al. Chem Senses, 2015 May. PMID 25687947, Free PMC Article
  5. Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes. Hosono C, et al. Nat Cell Biol, 2015 Dec. PMID 26551273

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables tRNA dimethylallyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables tRNA dimethylallyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in tRNA modification IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in tRNA processing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG31381-PA
CG31381-PB
NP_001189283.1
NP_733057.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    24877045..24878827
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_170178.3 → NP_733057.1  uncharacterized protein Dmel_CG31381, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_733057.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IMV0
    Related
    FBpp0084088
    Conserved Domains (3) summary
    PLN02748
    Location:1 → 446
    PLN02748; tRNA dimethylallyltransferase
    PRK00091
    Location:4 → 337
    miaA; tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed
    pfam12171
    Location:401 → 426
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding

  2. NM_001202354.2 → NP_001189283.1  uncharacterized protein Dmel_CG31381, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001189283.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IMV0
    Conserved Domains (3) summary
    PLN02748
    Location:1 → 446
    PLN02748; tRNA dimethylallyltransferase
    PRK00091
    Location:4 → 337
    miaA; tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed
    pfam12171
    Location:401 → 426
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8IMV0 Q8IMV0

Gene LinkOut

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