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ceh-1 Homeobox protein ceh-1 [ Caenorhabditis elegans ]

Gene ID: 191614, updated on 2-Nov-2024

Summary

Official Symbol
ceh-1
Official Full Name
Homeobox protein ceh-1
Primary source
WormBase:WBGene00000428
Locus tag
CELE_F16H11.4
See related
AllianceGenome:WB:WBGene00000428
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in DVC; lateral ganglion; and seam cell. Orthologous to human NKX1-1 (NK1 homeobox 1) and NKX1-2 (NK1 homeobox 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See ceh-1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
4
Sequence:
Chromosome: X; NC_003284.9 (4653167..4654157, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Equilibrative nucleoside transporter 1 Neighboring gene ncRNA Neighboring gene Nuclear Hormone Receptor family Neighboring gene Major facilitator superfamily domain-containing protein 12

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Homeobox protein ceh-1
NP_508796.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    4653167..4654157 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_076395.7NP_508796.2  Homeobox protein ceh-1 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P53547
    Conserved Domains (2) summary
    COG5576
    Location:2118
    COG5576; Homeodomain-containing transcription factor [Transcription]
    pfam00046
    Location:4496
    Homeobox; Homeobox domain