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W03G11.3 Putative alpha-L-fucosidase [ Caenorhabditis elegans ]

Gene ID: 189173, updated on 12-Jun-2024

Summary

Gene symbol
W03G11.3
Gene description
Putative alpha-L-fucosidase
Locus tag
CELE_W03G11.3
See related
AllianceGenome:WB:WBGene00012225
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable alpha-L-fucosidase activity. Predicted to be involved in fucose metabolic process and glycoside catabolic process. Predicted to be active in lysosome. Human ortholog(s) of this gene implicated in fucosidosis. Orthologous to several human genes including FUCA2 (alpha-L-fucosidase 2). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See W03G11.3 in Genome Data Viewer
Location:
chromosome: X
Exon count:
11
Sequence:
Chromosome: X; NC_003284.9 (12100191..12103812, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein Neighboring gene tRNA-Lys

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables alpha-L-fucosidase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables alpha-L-fucosidase activity IEA
Inferred from Electronic Annotation
more info
 
enables fucosidase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity, acting on glycosyl bonds IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in fucose metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in fucose metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in glycoside catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in lysosome IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Putative alpha-L-fucosidase
NP_510020.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    12100191..12103812 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_077619.6NP_510020.2  Putative alpha-L-fucosidase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_510020.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P49713
    Conserved Domains (2) summary
    smart00812
    Location:12377
    Alpha_L_fucos; Alpha-L-fucosidase
    COG3669
    Location:44355
    AfuC; Alpha-L-fucosidase [Carbohydrate transport and metabolism]