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M110.7 Putative patatin-like phospholipase domain-containing protein M110.7 [ Caenorhabditis elegans ]

Gene ID: 187474, updated on 2-Nov-2024

Summary

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Official Symbol
M110.7
Official Full Name
Putative patatin-like phospholipase domain-containing protein M110.7
Primary source
WormBase:WBGene00010915
Locus tag
CELE_M110.7
See related
AllianceGenome:WB:WBGene00010915
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable lysophospholipase activity. Predicted to be involved in lipid catabolic process. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in Boucher-Neuhauser syndrome; Laurence-Moon syndrome; Oliver-McFarlane syndrome; and hereditary spastic paraplegia 39. Orthologous to human PNPLA6 (patatin like phospholipase domain containing 6) and PNPLA7 (patatin like phospholipase domain containing 7). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See M110.7 in Genome Data Viewer
Location:
chromosome: II
Exon count:
20
Sequence:
Chromosome: II; NC_003280.10 (8232789..8237252)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene MIF4G domain-containing protein Neighboring gene PID domain-containing protein Neighboring gene DUF148 domain-containing protein Neighboring gene ncRNA Neighboring gene Neuropeptide-Like Protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables lysophospholipase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables lysophospholipase activity IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in lipid catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Putative patatin-like phospholipase domain-containing protein M110.7
NP_495734.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    8232789..8237252
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_063333.4 → NP_495734.3  Putative patatin-like phospholipase domain-containing protein M110.7 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_495734.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q20023, Q21534
    Conserved Domains (4) summary
    COG0664
    Location:423 → 543
    Crp; cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]
    COG1752
    Location:756 → 1046
    RssA; Predicted acylesterase/phospholipase RssA, containd patatin domain [General function prediction only]
    cd00038
    Location:444 → 538
    CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
    cl11396
    Location:752 → 1040
    Patatin_and_cPLA2; Patatins and Phospholipases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q21534.3

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