U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Rrp1 ribosomal RNA processing 1 [ Mus musculus (house mouse) ]

Gene ID: 18114, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
Rrp1provided by MGI
Official Full Name
ribosomal RNA processing 1provided by MGI
Primary source
MGI:MGI:1203500
See related
Ensembl:ENSMUSG00000061032 AllianceGenome:MGI:1203500
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Nnp1; NNP-1
Summary
Predicted to be involved in rRNA processing. Predicted to be located in chromosome and nucleolus. Predicted to be part of preribosome, small subunit precursor. Predicted to be active in nucleus. Is expressed in several structures, including genitourinary system; gut; nervous system; sensory organ; and thymus. Orthologous to human RRP1 (ribosomal RNA processing 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in testis adult (RPKM 117.2), frontal lobe adult (RPKM 80.6) and 28 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Rrp1 in Genome Data Viewer
Location:
10 C1; 10 39.72 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (78236196..78248877, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (78400362..78413043, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40709 Neighboring gene STARR-positive B cell enhancer ABC_E10623 Neighboring gene LSM7 homolog, U6 small nuclear RNA associated pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:77862123-77862306 Neighboring gene microRNA 6907 Neighboring gene cystatin B Neighboring gene microRNA 6410

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The NNP-1 gene (D21S2056E), which encodes a novel nuclear protein, maps in close proximity to the cystatin B gene within the EPM1 and APECED critical region on 21q22.3. Jansen E, et al. Genomics, 1997 Jun 1. PMID 9192856
  2. High-resolution comparative physical mapping of mouse chromosome 10 in the region of homology with human chromosome 21. Cole SE, et al. Mamm Genome, 1999 Mar. PMID 10051316
  3. Combining global genome and transcriptome approaches to identify the candidate genes of small-effect quantitative trait loci in collagen-induced arthritis. Yu X, et al. Arthritis Res Ther, 2007. PMID 17244351, Free PMC Article
  4. Perfect conserved linkage across the entire mouse chromosome 10 region homologous to human chromosome 21. Wiltshire T, et al. Genome Res, 1999 Dec. PMID 10613844, Free PMC Article
  5. A gene expression map of human chromosome 21 orthologues in the mouse. Gitton Y, et al. Nature, 2002 Dec 5. PMID 12466855

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
located_in chromosome ISO
Inferred from Sequence Orthology
more info
  
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of preribosome, small subunit precursor IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
ribosomal RNA processing protein 1 homolog A
Names
RRP1-like protein
novel nuclear protein 1
nucleolar protein Nop52
protein NNP-1
ribosomal RNA processing 1 homolog

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_010925.3 → NP_035055.2  ribosomal RNA processing protein 1 homolog A

    See identical proteins and their annotated locations for NP_035055.2

    Status: VALIDATED

    Source sequence(s)
    AC160411
    Consensus CDS
    CCDS35961.1
    UniProtKB/Swiss-Prot
    O35712, P56183, Q9ERE1, Q9JI07, Q9JK67, Q9JKU2
    Related
    ENSMUSP00000058785.10, ENSMUST00000062678.11
    Conserved Domains (1) summary
    pfam05997
    Location:11 → 218
    Nop52; Nucleolar protein,Nop52

RNA

  1. NR_190469.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC160411

  2. NR_190470.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC160411

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    78236196..78248877 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006513338.4 → XP_006513401.1  ribosomal RNA processing protein 1 homolog A isoform X1

    See identical proteins and their annotated locations for XP_006513401.1

    UniProtKB/TrEMBL
    Q05CN2
    Conserved Domains (2) summary
    pfam05997
    Location:1 → 156
    Nop52; Nucleolar protein,Nop52
    cl30717
    Location:299 → 424
    InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P56183.2 GenPept UniProtKB/Swiss-Prot:P56183

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Chemical Information
Molecular Biology Databases
Research Materials
Tools