U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

sgca-1 CADG domain-containing protein;Dystroglycan-type cadherin-like domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 180946, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
sgca-1
Official Full Name
CADG domain-containing protein;Dystroglycan-type cadherin-like domain-containing protein
Primary source
WormBase:WBGene00019227
Locus tag
CELE_H22K11.4
See related
AllianceGenome:WB:WBGene00019227
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable calcium ion binding activity. Located in striated muscle dense body. Is expressed in anal depressor muscle; anal sphincter muscle; body wall musculature; and vulval muscle. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2D; muscular dystrophy; and myoclonic dystonia 11. Orthologous to human SGCA (sarcoglycan alpha) and SGCE (sarcoglycan epsilon). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See sgca-1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
10
Sequence:
Chromosome: X; NC_003284.9 (6787256..6789548, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Prion-like-(Q/N-rich)-domain-bearing protein Neighboring gene Glycoside hydrolase 35 catalytic domain-containing protein Neighboring gene Aspartic protease 3 Neighboring gene ncRNA

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
part_of sarcoglycan complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of sarcoglycan complex IEA
Inferred from Electronic Annotation
more info
  
located_in striated muscle dense body IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
CADG domain-containing protein;Dystroglycan-type cadherin-like domain-containing protein
NP_001360086.1
  • Confirmed by transcript evidence
NP_001360087.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    6787256..6789548 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001373338.3 → NP_001360086.1  Dystroglycan-type cadherin-like domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2L0C3
    Conserved Domains (2) summary
    smart00736
    Location:29 → 118
    CADG; Dystroglycan-type cadherin-like domains
    pfam05510
    Location:28 → 320
    Sarcoglycan_2; Sarcoglycan alpha/epsilon

  2. NM_001373339.3 → NP_001360087.1  CADG domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q1XFY3
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools