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F09G2.8 putative phospholipase D F09G2.8 [ Caenorhabditis elegans ]

Gene ID: 179105, updated on 28-Oct-2024

Summary

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Official Symbol
F09G2.8
Official Full Name
putative phospholipase D F09G2.8
Primary source
WormBase:WBGene00017316
Locus tag
CELE_F09G2.8
See related
AllianceGenome:WB:WBGene00017316
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable N-acylphosphatidylethanolamine-specific phospholipase D activity and phospholipase D activity. Predicted to be involved in lipid catabolic process. Predicted to be located in membrane. Is expressed in several structures, including arcade cell; intestine; nervous system; pharynx; and rectal gland cell. Human ortholog(s) of this gene implicated in spinocerebellar ataxia 46. Orthologous to human PLD3 (phospholipase D family member 3) and PLD4 (phospholipase D family member 4). [provided by Alliance of Genome Resources, Oct 2024]
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Genomic context

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See F09G2.8 in Genome Data Viewer
Location:
chromosome: V
Exon count:
7
Sequence:
Chromosome: V; NC_003283.11 (7188436..7193662, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Ligand-Gated ion Channel Neighboring gene putative cleavage and polyadenylation specificity factor subunit 2 Neighboring gene Phosphate transporter Neighboring gene AT hook Transcription Factor family Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. In Vivo Interaction Proteomics in Caenorhabditis elegans Embryos Provides New Insights into P Granule Dynamics. Chen JX, et al. Mol Cell Proteomics, 2016 May. PMID 26912668, Free PMC Article
  2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables N-acylphosphatidylethanolamine-specific phospholipase D activity IEA
Inferred from Electronic Annotation
more info
  
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables phospholipase D activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in lipid catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
putative phospholipase D F09G2.8
NP_001122905.1
  • Confirmed by transcript evidence
NP_001256080.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    7188436..7193662 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001269151.3 → NP_001256080.1  putative phospholipase D F09G2.8 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001256080.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O17405
    Conserved Domains (3) summary
    cd09106
    Location:129 → 275
    PLDc_vPLD3_4_5_like_1; Putative catalytic domain, repeat 1, of vertebrate phospholipases, PLD3, PLD4 and PLD5, viral envelope proteins K4 and p37, and similar proteins
    cd09107
    Location:329 → 509
    PLDc_vPLD3_4_5_like_2; Putative catalytic domain, repeat 2, of vertebrate phospholipases, PLD3, PLD4 and PLD5, viral envelope proteins K4 and p37, and similar proteins
    PHA02820
    Location:121 → 516
    PHA02820; phospholipase-D-like protein; Provisional

  2. NM_001129433.6 → NP_001122905.1  putative phospholipase D F09G2.8 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001122905.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    G4RZL0, G8JY27, O17405
    Conserved Domains (3) summary
    cd09106
    Location:167 → 313
    PLDc_vPLD3_4_5_like_1; Putative catalytic domain, repeat 1, of vertebrate phospholipases, PLD3, PLD4 and PLD5, viral envelope proteins K4 and p37, and similar proteins
    cd09107
    Location:367 → 547
    PLDc_vPLD3_4_5_like_2; Putative catalytic domain, repeat 2, of vertebrate phospholipases, PLD3, PLD4 and PLD5, viral envelope proteins K4 and p37, and similar proteins
    PHA02820
    Location:159 → 554
    PHA02820; phospholipase-D-like protein; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O17405.2

Gene LinkOut

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