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algn-5 Dolichyl-phosphate beta-glucosyltransferase;dolichyl-phosphate beta-glucosyltransferase [ Caenorhabditis elegans ]

Gene ID: 178822, updated on 2-Nov-2024

Summary

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Official Symbol
algn-5
Official Full Name
Dolichyl-phosphate beta-glucosyltransferase;dolichyl-phosphate beta-glucosyltransferase
Primary source
WormBase:WBGene00019276
Locus tag
CELE_H43I07.3
See related
AllianceGenome:WB:WBGene00019276
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable dolichyl-phosphate beta-glucosyltransferase activity. Predicted to be involved in protein N-linked glycosylation. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in body wall musculature; nervous system; and pharynx. Human ortholog(s) of this gene implicated in polycystic kidney disease 7. Orthologous to human ALG5 (ALG5 dolichyl-phosphate beta-glucosyltransferase). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See algn-5 in Genome Data Viewer
Location:
chromosome: V
Exon count:
7
Sequence:
Chromosome: V; NC_003283.11 (4195577..4199399)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Protein pid-5 Neighboring gene Aftiphilin clathrin-binding box domain-containing protein;Clathrin_bdg domain-containing protein;Transcription factor Neighboring gene Nuclear hormone receptor 114 Neighboring gene DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein Neighboring gene OPA3-like protein;Peroxin-14

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables dolichyl-phosphate beta-glucosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein N-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Dolichyl-phosphate beta-glucosyltransferase;dolichyl-phosphate beta-glucosyltransferase
NP_001317828.1
  • Confirmed by transcript evidence
NP_741523.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    4195577..4199399
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_171446.4 → NP_741523.1  dolichyl-phosphate beta-glucosyltransferase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741523.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8WSL9
    Conserved Domains (1) summary
    cd04188
    Location:85 → 307
    DPG_synthase; DPG_synthase is involved in protein N-linked glycosylation

  2. NM_001330840.3 → NP_001317828.1  Dolichyl-phosphate beta-glucosyltransferase [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A168H9F5
    Conserved Domains (1) summary
    cl11394
    Location:1 → 145
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold
Nucleotide Protein
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