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nabp-1 GTP_EFTU_D2 domain-containing protein;OB domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 177470, updated on 2-Nov-2024

Summary

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Official Symbol
nabp-1
Official Full Name
GTP_EFTU_D2 domain-containing protein;OB domain-containing protein
Primary source
WormBase:WBGene00015554
Locus tag
CELE_C06G3.8
See related
AllianceGenome:WB:WBGene00015554
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA binding activity. Predicted to be involved in double-strand break repair via homologous recombination; mitotic G2/M transition checkpoint; and response to ionizing radiation. Predicted to be part of SOSS complex. Orthologous to human NABP1 (nucleic acid binding protein 1) and NABP2 (nucleic acid binding protein 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See nabp-1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
4
Sequence:
Chromosome: IV; NC_003282.8 (7031559..7032559, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene adenosine deaminase Neighboring gene pseudo Neighboring gene E3 UFM1-protein ligase 1 homolog Neighboring gene Uncharacterized protein Neighboring gene Conserved oligomeric Golgi complex subunit 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Multiple ERK substrates execute single biological processes in Caenorhabditis elegans germ-line development. Arur S, et al. Proc Natl Acad Sci U S A, 2009 Mar 24. PMID 19264959, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in double-strand break repair via homologous recombination IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitotic G2/M transition checkpoint IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in response to ionizing radiation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of SOSS complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
GTP_EFTU_D2 domain-containing protein;OB domain-containing protein
NP_001368394.1
  • Confirmed by transcript evidence
NP_501089.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    7031559..7032559 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_068688.8 → NP_501089.1  OB domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_501089.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q17749
    Conserved Domains (1) summary
    cd04491
    Location:18 → 95
    SoSSB_OBF; SoSSB_OBF: A subfamily of OB folds similar to the OB fold of the crenarchaeote Sulfolobus solfataricus single-stranded (ss) DNA-binding protein (SSoSSB). SSoSSB has a single OB fold, and it physically and functionally interacts with RNA polymerase. In ...

  2. NM_001380301.1 → NP_001368394.1  GTP_EFTU_D2 domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    V6CLM8
    Conserved Domains (1) summary
    cl09930
    Location:1 → 42
    RPA_2b-aaRSs_OBF_like; Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold.
Nucleotide Protein
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