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snf-3 [ Caenorhabditis elegans ]

Gene ID: 173493, updated on 22-Aug-2024

Summary

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Official Symbol
snf-3
Primary source
WormBase:WBGene00004902
Locus tag
CELE_T13B5.1
See related
AllianceGenome:WB:WBGene00004902
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables amino-acid betaine transmembrane transporter activity. Involved in amino-acid betaine transport. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in neuron projection. Predicted to be integral component of plasma membrane. Is expressed in excretory cell; hypodermis; nervous system; and vulval cell. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See snf-3 in Genome Data Viewer
Location:
chromosome: II
Exon count:
9
Sequence:
Chromosome: II; NC_003280.10 (1092006..1097899)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene C6 domain-containing protein Neighboring gene tRNA Neighboring gene Histidine acid phosphatase Neighboring gene Leishmanolysin-like peptidase Neighboring gene tRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Betaine acts on a ligand-gated ion channel in the nervous system of the nematode C. elegans. Peden AS, et al. Nat Neurosci, 2013 Dec. PMID 24212673, Free PMC Article
  2. The Caenorhabditis elegans snf-11 gene encodes a sodium-dependent GABA transporter required for clearance of synaptic GABA. Mullen GP, et al. Mol Biol Cell, 2006 Jul. PMID 16641366, Free PMC Article
  3. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables amino-acid betaine transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables gamma-aminobutyric acid:sodium:chloride symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables symporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in amino acid transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in amino-acid betaine transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in gamma-aminobutyric acid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in neurotransmitter transport IEA
Inferred from Electronic Annotation
more info
  
involved_in sodium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Sodium- and chloride-dependent betaine transporter
NP_493910.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    1092006..1097899
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_061509.10 → NP_493910.2  Sodium- and chloride-dependent betaine transporter [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_493910.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    G5EBN9
    Conserved Domains (1) summary
    cd11496
    Location:30 → 571
    SLC6sbd-TauT-like; Na(+)- and Cl(-)-dependent taurine transporter TauT, and related proteins; solute-binding domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
G5EBN9.1

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