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mps-2 MiRP K channel accessory Subunit [ Caenorhabditis elegans ]

Gene ID: 173419, updated on 18-Sep-2024

Summary

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Official Symbol
mps-2
Official Full Name
MiRP K channel accessory Subunit
Primary source
WormBase:WBGene00019282
Locus tag
CELE_K01A2.8
See related
AllianceGenome:WB:WBGene00019282
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables potassium channel regulator activity. Involved in regulation of chemotaxis and regulation of potassium ion transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including coelomocyte; enteric muscle; intestine; lateral ganglion; and rectal muscle. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See mps-2 in Genome Data Viewer
Location:
chromosome: II
Exon count:
5
Sequence:
Chromosome: II; NC_003280.10 (309479..312157, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene AB hydrolase-1 domain-containing protein Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein Neighboring gene DUF2231 domain-containing protein;Transmembrane protein Neighboring gene pseudo Neighboring gene MiRP K channel accessory Subunit

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dual Role of an mps-2/KCNE-Dependent Pathway in Long-Term Memory and Age-Dependent Memory Decline. Fenyves BG, et al. Curr Biol, 2021 Feb 8. PMID 33259792
  2. An evolutionarily conserved family of accessory subunits of K+ channels. Cai SQ, et al. Cell Biochem Biophys, 2006. PMID 16943626
  3. A family of K+ channel ancillary subunits regulate taste sensitivity in Caenorhabditis elegans. Park KH, et al. J Biol Chem, 2005 Jun 10. PMID 15799965
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables potassium channel regulator activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in long-term memory IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of chemotaxis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of potassium ion transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of potassium ion transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
MiRP K channel accessory Subunit
NP_001033335.1
  • Product from WormBase gene class mps;
    Confirmed by transcript evidence
NP_001379579.1
  • Product from WormBase gene class mps;
    Confirmed by transcript evidence
NP_001379580.1
  • Product from WormBase gene class mps;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    309479..312157 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001392992.1 → NP_001379580.1  MiRP K channel accessory Subunit [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q86S20

  2. NM_001392991.1 → NP_001379579.1  MiRP K channel accessory Subunit [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q56VR8, Q9TZ55

  3. NM_001038246.6 → NP_001033335.1  MiRP K channel accessory Subunit [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001033335.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q56VR8, Q56VR9
Nucleotide Protein
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