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his-68 Histone H2A [ Caenorhabditis elegans ]

Gene ID: 172860, updated on 2-Nov-2024

Summary

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Official Symbol
his-68
Official Full Name
Histone H2A
Primary source
WormBase:WBGene00001942
Locus tag
CELE_T23D8.6
See related
AllianceGenome:WB:WBGene00001942
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is expressed in germ line. Orthologous to several human genes including H2AX (H2A.X variant histone). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See his-68 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003279.8 (9989132..9989515)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Histone H4 Neighboring gene Protein argonaute-2 Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structural Insights into ceNAP1 Chaperoning Activity toward ceH2A-H2B. Liu Y, et al. Structure, 2019 Dec 3. PMID 31653339
  2. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
  3. The RNA-binding protein repertoire of Arabidopsis thaliana. Marondedze C, et al. Sci Rep, 2016 Jul 11. PMID 27405932, Free PMC Article
  4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of chromatin IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of nucleosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Histone H2A
NP_492642.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    9989132..9989515
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_060241.6 → NP_492642.1  Histone H2A [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492642.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P09588, Q7JKF5
    Conserved Domains (1) summary
    PTZ00017
    Location:18 → 127
    PTZ00017; histone H2A; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P09588.2

Gene LinkOut

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Chemical Information
Molecular Biology Databases
Research Materials
Miscellaneous