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cogc-3 Conserved oligomeric Golgi complex subunit 3;Conserved oligomeric Golgi complex subunit 3 C-terminal domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 171867, updated on 2-Nov-2024

Summary

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Official Symbol
cogc-3
Official Full Name
Conserved oligomeric Golgi complex subunit 3;Conserved oligomeric Golgi complex subunit 3 C-terminal domain-containing protein
Primary source
WormBase:WBGene00022121
Locus tag
CELE_Y71F9AM.4
See related
AllianceGenome:WB:WBGene00022121
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in gonad morphogenesis and regulation of cell migration. Located in Golgi apparatus and endoplasmic reticulum. Is expressed in intestine; pharynx; seam cell; and vulva. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type II. Orthologous to human COG3 (component of oligomeric golgi complex 3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See cogc-3 in Genome Data Viewer
Location:
chromosome: I
Exon count:
14
Sequence:
Chromosome: I; NC_003279.8 (2931461..2947106)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Translocon-associated protein subunit alpha Neighboring gene NTF2-related export protein Neighboring gene ncRNA Neighboring gene Conserved secreted protein Neighboring gene Neuropeptide-Like Protein Neighboring gene ncRNA Neighboring gene Secreted protein Neighboring gene Neurexin-related protein bam-2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. C. elegans as a model system to study the function of the COG complex in animal development. Kubota Y, et al. Biol Chem, 2006 Aug. PMID 16895472
  2. Serum- and Glucocorticoid-Inducible Kinase-1 (SGK-1) Plays a Role in Membrane Trafficking in Caenorhabditis elegans. Zhu M, et al. PLoS One, 2015. PMID 26115433, Free PMC Article
  3. The conserved oligomeric Golgi complex acts in organ morphogenesis via glycosylation of an ADAM protease in C. elegans. Kubota Y, et al. Development, 2006 Jan. PMID 16354716
  4. RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans. LeGendre JB, et al. J Biol Chem, 2013 Jan 25. PMID 23195953, Free PMC Article
  5. A protein domain-based interactome network for C. elegans early embryogenesis. Boxem M, et al. Cell, 2008 Aug 8. PMID 18692475, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in Golgi organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in gonad morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in intra-Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of cell migration IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
part_of Golgi transport complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cis-Golgi network IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Conserved oligomeric Golgi complex subunit 3;Conserved oligomeric Golgi complex subunit 3 C-terminal domain-containing protein
NP_001021806.1
  • Confirmed by transcript evidence
NP_001380050.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    2931461..2947106
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001026635.5 → NP_001021806.1  Conserved oligomeric Golgi complex subunit 3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001021806.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q2V0X4, Q6AW08
    Conserved Domains (1) summary
    pfam04136
    Location:79 → 205
    Sec34; Sec34-like family

  2. NM_001393155.1 → NP_001380050.1  Conserved oligomeric Golgi complex subunit 3 C-terminal domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    H2L0S2
Nucleotide Protein
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