U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

C53D5.5 Gamma-glutamyltranspeptidase 1 [ Caenorhabditis elegans ]

Gene ID: 171619, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
C53D5.5
Official Full Name
Gamma-glutamyltranspeptidase 1
Primary source
WormBase:WBGene00016906
Locus tag
CELE_C53D5.5
See related
AllianceGenome:WB:WBGene00016906
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable glutathione hydrolase activity. Predicted to be involved in glutathione catabolic process. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in gamma-glutamyl transpeptidase deficiency. Orthologous to several human genes including GGT1 (gamma-glutamyltransferase 1) and GGT2P (gamma-glutamyltransferase 2, pseudogene). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See C53D5.5 in Genome Data Viewer
Location:
chromosome: I
Exon count:
7
Sequence:
Chromosome: I; NC_003279.8 (305811..310790, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene RING-CH-type domain-containing protein Neighboring gene C2H2-type domain-containing protein Neighboring gene FAM69 protein-kinase domain-containing protein Neighboring gene Importin N-terminal domain-containing protein Neighboring gene pseudo

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
  2. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
  3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables glutathione hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glutathione hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in glutathione catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in glutathione catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Gamma-glutamyltranspeptidase 1
NP_001364826.1
  • Confirmed by transcript evidence
NP_490714.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    305811..310790 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_058313.7 → NP_490714.1  Gamma-glutamyltranspeptidase 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_490714.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9N5V4
    Conserved Domains (1) summary
    pfam01019
    Location:119 → 633
    G_glu_transpept; Gamma-glutamyltranspeptidase

  2. NM_001377821.2 → NP_001364826.1  Gamma-glutamyltranspeptidase 1 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    V6CLP9
    Conserved Domains (1) summary
    pfam01019
    Location:72 → 587
    G_glu_transpept; Gamma-glutamyltranspeptidase
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous