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ORF7b ORF7b protein [ SARS coronavirus Tor2 ]

Gene ID: 1489675, updated on 7-Jul-2024

Summary

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Gene symbol
ORF7b
Gene description
ORF7b protein
Locus tag
sars7b
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
SARS coronavirus Tor2 (isolate: Tor2, nat-host: Homo sapiens; patient #2 with severe acute respiratory syndrome (SARS))
Lineage
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes; Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae; Betacoronavirus; Sarbecovirus
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Genomic context

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Sequence:
NC_004718.3 (27638..27772)

NC_004718.3Genomic Context describing neighboring genes Neighboring gene ORF3b protein Neighboring gene small envelope protein Neighboring gene membrane glycoprotein M Neighboring gene ORF6 protein Neighboring gene ORF7a protein Neighboring gene ORF8a protein Neighboring gene ORF8b protein Neighboring gene ORF9b protein Neighboring gene ORF9a protein;nucleocapsid protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_004718.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The transmembrane domain of the severe acute respiratory syndrome coronavirus ORF7b protein is necessary and sufficient for its retention in the Golgi complex. Schaecher SR, et al. J Virol, 2008 Oct. PMID 18632859, Free PMC Article
  2. The ORF7b protein of severe acute respiratory syndrome coronavirus (SARS-CoV) is expressed in virus-infected cells and incorporated into SARS-CoV particles. Schaecher SR, et al. J Virol, 2007 Jan. PMID 17079322, Free PMC Article
  3. Structure, expression, and intracellular localization of the SARS-CoV accessory proteins 7a and 7b. Pekosz A, et al. Adv Exp Med Biol, 2006. PMID 17037516, Free PMC Article
  4. Interactions among SARS-CoV accessory proteins revealed by bimolecular fluorescence complementation assay. Kong J, et al. Acta Pharm Sin B, 2015 Sep. PMID 26579480, Free PMC Article
  5. Genome-wide analysis of protein-protein interactions and involvement of viral proteins in SARS-CoV replication. Pan J, et al. PLoS One, 2008 Oct 1. PMID 18827877, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. the Golgi complex retention signal of the ORF7b protein resides solely within the transmembrane domain
    Title: The transmembrane domain of the severe acute respiratory syndrome coronavirus ORF7b protein is necessary and sufficient for its retention in the Golgi complex.
  2. analysis of SARS-CoV accessory proteins 7a and 7b
    Title: Structure, expression, and intracellular localization of the SARS-CoV accessory proteins 7a and 7b.
  3. ORF7b protein is expressed in virus-infected cell lysates,localizes to the Golgi compartment and is incorporated into SARS-CoV particles. [ORF7b]
    Title: The ORF7b protein of severe acute respiratory syndrome coronavirus (SARS-CoV) is expressed in virus-infected cells and incorporated into SARS-CoV particles.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General protein information

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Preferred Names
ORF7b protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004718.3 Reference assembly

    Range
    27638..27772
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_009825058.1 ORF7b protein [SARS coronavirus Tor2]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q7TFA1, Q7TLC9
    UniProtKB/TrEMBL
    A0A3G5BJ49, B8Q8Q9, B8Q8S0, B8Q8T2, B8Q8U3, C4P6R4, D2E1D9, D2E1F4, D2E228, D2E272, D3KDN2, Q19QW3, Q1EFM5, Q1EFN8, Q3S2B8, Q3ZTB8, Q3ZTD3, Q3ZTE6, Q4JDP7, Q4JDR0, Q6S8D0, Q6S8E4, Q6SRQ4, Q6SRQ9, Q6SRR4, Q6SRR9, Q6SRS4, Q6SRS9, Q6SRT4, Q6SRT9, Q6SRU4, Q6SRU9, Q6SRV4, Q6SRV9, Q6SRW4, Q6SRW9, Q6SRX4, Q6SRX9, Q6SRY4, Q6SRY9, Q6T1D5, Q6T9E5, Q6TPE2, Q76XZ8, Q7T695, Q7T6Q7, Q7T6R0, Q7T6R4, Q7T6R8, Q7T6S2, Q7TA16, Q7TA24
    Conserved Domains (1) summary
    cd21635
    Location:1 → 44
    ORF7b_SARS-CoV-like; Severe Acute Respiratory Syndrome coronavirus structural accessory protein ORF7b and related proteins
Nucleotide Protein
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