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TRIM16L tripartite motif containing 16 like (pseudogene) [ Homo sapiens (human) ]

Gene ID: 147166, updated on 5-Mar-2024

Summary

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Official Symbol
TRIM16Lprovided by HGNC
Official Full Name
tripartite motif containing 16 like (pseudogene)provided by HGNC
Primary source
HGNC:HGNC:32670
See related
Ensembl:ENSG00000291110 AllianceGenome:HGNC:32670
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TRIM70
Summary
Located in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in esophagus (RPKM 13.7), gall bladder (RPKM 5.6) and 24 other tissues See more
Orthologs
all
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Genomic context

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Location:
17p11.2
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (18697998..18736112)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (18644447..18682266)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (18601311..18639425)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:18553597-18554097 Neighboring gene PAIP1 pseudogene 2 Neighboring gene zinc finger protein 286B (pseudogene) Neighboring gene forkhead box O3B Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:18585117-18585622 Neighboring gene ubiquitin conjugating enzyme E2 S pseudogene 2 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8279 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:18601479-18602036 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr17:18621593-18622463 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr17:18622464-18623334 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:18624898-18625462 Neighboring gene Sharpr-MPRA regulatory region 2370 Neighboring gene F-box and WD repeat domain containing 10 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr17:18673855-18674355 Neighboring gene trans-golgi network vesicle protein 23 homolog B Neighboring gene NANOG hESC enhancer GRCh37_chr17:18706781-18707432

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. TRIM59 Promotes the Proliferation and Migration of Non-Small Cell Lung Cancer Cells by Upregulating Cell Cycle Related Proteins. Zhan W, et al. PLoS One, 2015. PMID 26599082, Free PMC Article
  2. SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity. Shi P, et al. J Immunol, 2020 Jul 1. PMID 32393512
  3. TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing. Demirdizen E, et al. Neuro Oncol, 2023 Jun 2. PMID 36215168, Free PMC Article
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article
  5. The BioPlex Network: A Systematic Exploration of the Human Interactome. Huttlin EL, et al. Cell, 2015 Jul 16. PMID 26186194, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Other Names

  • tripartite motif protein 70
  • tripartite motif-containing 16-like
  • tripartite motif-containing protein 16-like protein
  • tripartite motif-containing protein 70

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_172633.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC026271, AC107982

  2. NR_172634.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC026271, AC107982
    Related
    ENST00000572555.5

  3. NR_172635.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC026271, AC107982

  4. NR_172636.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC026271
    Related
    ENST00000449697.9

  5. NR_172637.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC026271, AC107982

  6. NR_172638.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC026271, AC107982

  7. NR_172639.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC107982

  8. NR_172640.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC107982

  9. NR_172641.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC107982
    Related
    ENST00000641936.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

    Range
    18697998..18736112
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060941.1 Alternate T2T-CHM13v2.0

    Range
    18644447..18682266
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001037330.3: Suppressed sequence

    Description
    NM_001037330.3: This RefSeq was removed because it is now thought that this gene is a pseudogene.

  2. NM_001353219.2: Suppressed sequence

    Description
    NM_001353219.2: This RefSeq was removed because it is now thought that this gene is a pseudogene.

  3. NM_001353220.2: Suppressed sequence

    Description
    NM_001353220.2: This RefSeq was removed because it is now thought that this gene is a pseudogene.

  4. NM_001353221.2: Suppressed sequence

    Description
    NM_001353221.2: This RefSeq was removed because it is now thought that this gene is a pseudogene.

  5. NM_001353222.2: Suppressed sequence

    Description
    NM_001353222.2: This RefSeq was removed because it is now thought that this gene is a pseudogene.

  6. NM_001353223.2: Suppressed sequence

    Description
    NM_001353223.2: This RefSeq was removed because it is now thought that this gene is a pseudogene.

  7. NM_001353224.2: Suppressed sequence

    Description
    NM_001353224.2: This RefSeq was removed because it is now thought that this gene is a pseudogene.

  8. NM_001353225.2: Suppressed sequence

    Description
    NM_001353225.2: This RefSeq was removed because it is now thought that this gene is a pseudogene.

  9. NM_001353226.2: Suppressed sequence

    Description
    NM_001353226.2: This RefSeq was removed because it is now thought that this gene is a pseudogene.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q309B1.3 GenPept UniProtKB/Swiss-Prot:Q309B1

Gene LinkOut

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