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MCO6 Mco6p [ Saccharomyces cerevisiae S288C ]

Gene ID: 1466466, updated on 3-Nov-2024

Summary

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Official Symbol
MCO6
Official Full Name
Mco6p
Primary source
SGD:S000028522
Locus tag
YJL127C-B
See related
AllianceGenome:SGD:S000028522; FungiDB:YJL127C-B; VEuPathDB:YJL127C-B
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
YJL127C-A
Summary
Involved in mitochondrial outer membrane translocase complex assembly. Located in mitochondrial outer membrane. Part of SAM complex. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See MCO6 in Genome Data Viewer
Location:
chromosome: X
Exon count:
1
Sequence:
Chromosome: X; NC_001142.9 (181551..181709, complement)

Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene Trk1p Neighboring gene mitogen-activated protein kinase kinase PBS2 Neighboring gene Spt10p Neighboring gene putative hydrolase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001142.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Role of the small protein Mco6 in the mitochondrial sorting and assembly machinery. Busto JV, et al. Cell Rep, 2024 Mar 26. PMID 38377000
  2. Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Brachat S, et al. Genome Biol, 2003. PMID 12844361, Free PMC Article
  3. Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale. Morgenstern M, et al. Cell Rep, 2017 Jun 27. PMID 28658629, Free PMC Article
  4. The zinc-finger transcription factor Sfp1 imprints specific classes of mRNAs and links their synthesis to cytoplasmic decay. Kelbert M, et al. Elife, 2024 Oct 2. PMID 39356734, Free PMC Article
  5. Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X. Galibert F, et al. EMBO J, 1996 May 1. PMID 8641269, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in mitochondrial outer membrane translocase complex assembly IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in mitochondrial outer membrane translocase complex assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in outer mitochondrial membrane organization IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of SAM complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrial outer membrane HDA PubMed 
located_in mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Mco6p
NP_878103.1
  • Mitochondrial outer membrane protein protein; co-assembles with Mdm10p into the mitochondrial sorting and assembly machinery (SAM) complex and cooperates with Mdm10p in the assembly of the translocase of the outer membrane (TOM) complex; identified based on homology to the filamentous fungus, Ashbya gossypii; SWAT-GFP and seamless-GFP fusion proteins localize to the mitochondria

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001142.9 Reference assembly

    Range
    181551..181709 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184532.1 → NP_878103.1  TPA: Mco6p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_878103.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VW58, Q3E828
    UniProtKB/TrEMBL
    A6ZQK3, B3LPZ1, C7GQ01, C8ZB91, G2WGP5
    Conserved Domains (1) summary
    pfam17237
    Location:5 → 48
    DUF5310; Family of unknown function (DUF5310)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3E828.1

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