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HRVBgp1 polyprotein [ rhinovirus B14 ]

Gene ID: 1461213, updated on 18-Aug-2023

Summary

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Gene symbol
HRVBgp1
Gene description
polyprotein
Locus tag
HRVBgp1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
rhinovirus B14
Lineage
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes; Picornavirales; Picornaviridae; Ensavirinae; Enterovirus
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Genomic context

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Sequence:
NC_001490.1 (629..7168)

NC_001490.1Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001490.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Selective Removal of FG Repeat Domains from the Nuclear Pore Complex by Enterovirus 2A(pro). Park N, et al. J Virol, 2015 Nov. PMID 26311873, Free PMC Article
  2. Antibodies to the buried N terminus of rhinovirus VP4 exhibit cross-serotypic neutralization. Katpally U, et al. J Virol, 2009 Jul. PMID 19403680, Free PMC Article
  3. The complete nucleotide sequence of a common cold virus: human rhinovirus 14. Stanway G, et al. Nucleic Acids Res, 1984 Oct 25. PMID 6093056, Free PMC Article
  4. Molecular cloning and complete sequence determination of RNA genome of human rhinovirus type 14. Callahan PL, et al. Proc Natl Acad Sci U S A, 1985 Feb. PMID 2983312, Free PMC Article
  5. RIPK1 Is Cleaved by 3C Protease of Rhinovirus A and B Strains and Minor and Major Groups. Croft SN, et al. Viruses, 2021 Nov 30. PMID 34960671, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. RIPK1 Is Cleaved by 3C Protease of Rhinovirus A and B Strains and Minor and Major Groups.
    Title: RIPK1 Is Cleaved by 3C Protease of Rhinovirus A and B Strains and Minor and Major Groups.
  2. The selective removal of Nup FG repeat domains by Enterovirus 2a(pro) leads to increased nuclear pore complex permeability and the inhibition of certain transport pathways.
    Title: Selective Removal of FG Repeat Domains from the Nuclear Pore Complex by Enterovirus 2A(pro).
  3. Epitope mapping of the N-terminal 30 residues of VP4 suggests that it adopts a nonlinear conformation.
    Title: Antibodies to the buried N terminus of rhinovirus VP4 exhibit cross-serotypic neutralization.
Submit: New GeneRIF Correction

General protein information

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Preferred Names
polyprotein
Names
1A (VP4)
1B (VP2)
1C (VP3)
1D (VP1)
2A (P2-A)
2B (P2-B)
2C (P2-C)
3A (P3-A)
3B (VPg)
protease 3C
3D

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001490.1 Reference assembly

    Range
    629..7168
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_041009.1 polyprotein [rhinovirus B14]

    See identical proteins and their annotated locations for NP_041009.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P03303, Q82083, Q82123, Q84736, Q84737, Q84738, Q84739, Q84740, Q84741, Q84774, Q84775, Q84776, Q84777, Q84778, Q84779, Q89441, Q89649, Q89763, Q89883
    Conserved Domains (9) summary
    cd00205
    Location:374 → 556
    rhv_like; Picornavirus capsid protein domain_like. Picornaviruses are non-enveloped plus-strand ssRNA animal viruses with icosahedral capsids composed of 60 copies each of 4 virus encoded proteins; alignment includes picornaviridae, like poliovirus, hepatitis A ...
    pfam00073
    Location:93 → 299
    Rhv; picornavirus capsid protein
    pfam00548
    Location:1538 → 1702
    Peptidase_C3; 3C cysteine protease (picornain 3C)
    pfam00910
    Location:1225 → 1323
    RNA_helicase; RNA helicase
    pfam00947
    Location:874 → 1000
    Pico_P2A; Picornavirus core protein 2A
    pfam01552
    Location:1002 → 1100
    Pico_P2B; Picornavirus 2B protein
    pfam02226
    Location:2 → 69
    Pico_P1A; Picornavirus coat protein (VP4)
    pfam08727
    Location:1430 → 1486
    P3A; Poliovirus 3A protein like
    cl02808
    Location:1736 → 2177
    RT_like; RT_like: Reverse transcriptase (RT, RNA-dependent DNA polymerase)_like family. An RT gene is usually indicative of a mobile element such as a retrotransposon or retrovirus. RTs occur in a variety of mobile elements, including retrotransposons, ...

  2. NP_740515.1 1A (VP4)

    UniProtKB/TrEMBL
    Q80SI7, Q80SQ4
    Conserved Domains (1) summary
    pfam02226
    Location:2 → 69
    Pico_P1A; Picornavirus coat protein (VP4)

  3. NP_740516.1 1B (VP2)

    Conserved Domains (1) summary
    pfam00073
    Location:24 → 230
    Rhv; picornavirus capsid protein

  4. NP_740517.1 1C (VP3)

    Conserved Domains (1) summary
    cd00205
    Location:43 → 225
    rhv_like; Picornavirus capsid protein domain_like. Picornaviruses are non-enveloped plus-strand ssRNA animal viruses with icosahedral capsids composed of 60 copies each of 4 virus encoded proteins; alignment includes picornaviridae, like poliovirus, hepatitis A ...

  5. NP_740518.1 1D (VP1)

    UniProtKB/TrEMBL
    Q7T650
    Conserved Domains (1) summary
    pfam00073
    Location:47 → 203
    Rhv; picornavirus capsid protein

  6. NP_740519.1 2A (P2-A)

    Conserved Domains (1) summary
    pfam00947
    Location:18 → 144
    Pico_P2A; Picornavirus core protein 2A

  7. NP_740520.1 2B (P2-B)

    Conserved Domains (1) summary
    pfam01552
    Location:1 → 97
    Pico_P2B; Picornavirus 2B protein

  8. NP_740521.1 2C (P2-C)

    Conserved Domains (2) summary
    smart00382
    Location:125 → 249
    AAA; ATPases associated with a variety of cellular activities
    pfam00910
    Location:126 → 224
    RNA_helicase; RNA helicase

  9. NP_740522.1 3A (P3-A)

    Conserved Domains (1) summary
    pfam08727
    Location:1 → 57
    P3A; Poliovirus 3A protein like

  10. NP_740523.1 3B (VPg)

  11. NP_740524.1 protease 3C

    Conserved Domains (1) summary
    pfam00548
    Location:1 → 165
    Peptidase_C3; 3C cysteine protease (picornain 3C)

  12. NP_740525.1 3D

    Conserved Domains (1) summary
    cl02808
    Location:17 → 458
    RT_like; RT_like: Reverse transcriptase (RT, RNA-dependent DNA polymerase)_like family. An RT gene is usually indicative of a mobile element such as a retrotransposon or retrovirus. RTs occur in a variety of mobile elements, including retrotransposons, ...
Nucleotide Protein
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