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orf5 NS5 protein [ Middle East respiratory syndrome-related coronavirus ]

Gene ID: 14254598, updated on 18-Aug-2023

Summary

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Gene symbol
orf5
Gene description
NS5 protein
Locus tag
G128_gp06
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Middle East respiratory syndrome-related coronavirus (strain: HCoV-EMC, isolate: HCoV-EMC/2012, nat-host: Homo sapiens)
Lineage
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes; Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae; Betacoronavirus; Merbecovirus
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Genomic context

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Sequence:
NC_019843.3 (26840..27514)

NC_019843.3Genomic Context describing neighboring genes Neighboring gene NS3 protein Neighboring gene NS4A protein Neighboring gene NS4B protein Neighboring gene envelope protein Neighboring gene membrane protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_019843.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Middle East Respiratory Syndrome Coronavirus Gene 5 Modulates Pathogenesis in Mice. Gutierrez-Alvarez J, et al. J Virol, 2021 Jan 13. PMID 33144319, Free PMC Article
  2. Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans. van Boheemen S, et al. mBio, 2012 Nov 20. PMID 23170002, Free PMC Article
  3. Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. Gordon DE, et al. Science, 2020 Dec 4. PMID 33060197, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Middle East Respiratory Syndrome Coronavirus Gene 5 Modulates Pathogenesis in Mice.
    Title: Middle East Respiratory Syndrome Coronavirus Gene 5 Modulates Pathogenesis in Mice.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

General protein information

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Preferred Names
NS5 protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_019843.3 Reference assembly

    Range
    26840..27514
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_009047208.1 NS5 protein [Middle East respiratory syndrome-related coronavirus]

    See identical proteins and their annotated locations for YP_009047208.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    K9N7D2
    UniProtKB/TrEMBL
    A0A023W117, A0A0R7E433, A0A0R9UR29, A0A0S3IUV3, A0A0U2GMJ3, A0A0U2GMP6, A0A0U4A3B2, A0A140AQ44, A0A140HF78, A0A291I622, A0A291I6C6, A0A2H4GWN8, A0A345F112, A0A455M3B7, A0A4D6YZT2, A0A6M2ZJE4, A0A7D5JDR2, A0A7S5GEY8, A0A858Z741, K0BUR3, M1RUQ6, M4SVF1, R9UQM6, T2BB75, W5ZZC9, W5ZZJ0, W6A0I1
    Conserved Domains (1) summary
    cd21645
    Location:3 → 222
    MERS-CoV-like_ORF5; Non-structural protein ORF5 from Middle East respiratory syndrome-related coronavirus and related betacoronaviruses in the C lineage
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
AFS88940.2

Gene LinkOut

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