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SYK spleen associated tyrosine kinase [ Mustela nigripes (black-footed ferret) ]

Gene ID: 132024902, updated on 11-Apr-2024

Summary

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Gene symbol
SYK
Gene description
spleen associated tyrosine kinase
See related
EnsemblRapid:ENSMNGG00000020092
Gene type
protein coding
RefSeq status
MODEL
Organism
Mustela nigripes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae; Mustelinae; Mustela
Orthologs
human mouse all
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Genomic context

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See SYK in Genome Data Viewer
Location:
chromosome: 9
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2023_09 current MUSNIG.SB6536 (GCF_022355385.1) 9 NC_081565.1 (90152909..90220680)

Chromosome 9 - NC_081565.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132025202 Neighboring gene DIRAS family GTPase 2 Neighboring gene basic proline-rich protein-like Neighboring gene uncharacterized LOC132025203 Neighboring gene nuclear factor, interleukin 3 regulated

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_081565.1 Chromosome 9 Reference MUSNIG.SB6536 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in B cell receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in adaptive immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in macrophage activation involved in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neutrophil activation involved in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of B cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of alpha-beta T cell proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of mast cell degranulation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of platelet aggregation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extrinsic component of cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase SYK

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_022355385.1-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference MUSNIG.SB6536 Primary Assembly

Genomic

  1. NC_081565.1 Reference MUSNIG.SB6536 Primary Assembly

    Range
    90152909..90220680
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059412113.1 → XP_059268096.1  tyrosine-protein kinase SYK isoform X3

  2. XM_059412112.1 → XP_059268095.1  tyrosine-protein kinase SYK isoform X2

    Related
    ENSMNGP00000028833.1, ENSMNGT00000036160.1

  3. XM_059412110.1 → XP_059268093.1  tyrosine-protein kinase SYK isoform X1

  4. XM_059412111.1 → XP_059268094.1  tyrosine-protein kinase SYK isoform X1

    Related
    ENSMNGP00000028821.1, ENSMNGT00000036148.1

  5. XM_059412109.1 → XP_059268092.1  tyrosine-protein kinase SYK isoform X1

Nucleotide Protein
Heading Accession and Version

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