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LOC130062774 ATAC-STARR-seq lymphoblastoid silent region 9571 [ Homo sapiens (human) ]

Gene ID: 130062774, updated on 12-Sep-2024

Summary

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Gene symbol
LOC130062774
Gene description
ATAC-STARR-seq lymphoblastoid silent region 9571
Gene type
biological region
Feature type(s)
regulatory: silencer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic sequence represents an accessible chromatin region that was validated as a silencer based on its ability to repress an origin of replication minimal core promoter by the ATAC-STARR-seq (assay for transposase-accessible chromatin with self-transcribing active regulatory region sequencing) massively parallel reporter assay (MPRA) in GM12878 lymphoblastoid cells. [provided by RefSeq, May 2023]
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Genomic context

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See LOC130062774 in Genome Data Viewer
Location:
chromosome: 18
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 18 NC_000018.10 (79395766..79396165)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 18 NC_060942.1 (79649764..79650163)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 18 NC_000018.9 (77155766..77156165)

Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene ATPase phospholipid transporting 9B (putative) Neighboring gene uncharacterized LOC124904332 Neighboring gene histidine-rich protein PFHRP-II-like Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr18:77121413-77122612 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr18:77138853-77139403 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr18:77140873-77141374 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:77152806-77153331 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:77153332-77153856 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9570 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13538 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:77156322-77156869 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9573 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9574 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13539 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr18:77165018-77165613 Neighboring gene H3K27ac hESC enhancer GRCh37_chr18:77166804-77167397 Neighboring gene ReSE screen-validated silencer GRCh37_chr18:77167420-77167581 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:77171165-77171680 Neighboring gene octapeptide-repeat protein T2 Neighboring gene uncharacterized LOC124904334 Neighboring gene nuclear factor of activated T cells 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr18:77203425-77204271

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ATAC-STARR-seq reveals transcription factor-bound activators and silencers within chromatin-accessible regions of the human genome. Hansen TJ, et al. Genome Res, 2022 Aug 25. PMID 35858748, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_195666.1 

    Range
    101..500
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000018.10 Reference GRCh38.p14 Primary Assembly

    Range
    79395766..79396165
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060942.1 Alternate T2T-CHM13v2.0

    Range
    79649764..79650163
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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