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LOC130056277 ATAC-STARR-seq lymphoblastoid active region 8881 [ Homo sapiens (human) ]

Gene ID: 130056277, updated on 12-Sep-2024

Summary

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Gene symbol
LOC130056277
Gene description
ATAC-STARR-seq lymphoblastoid active region 8881
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic sequence represents an accessible chromatin region that was validated as an enhancer based on its ability to activate an origin of replication minimal core promoter by the ATAC-STARR-seq (assay for transposase-accessible chromatin with self-transcribing active regulatory region sequencing) massively parallel reporter assay (MPRA) in GM12878 lymphoblastoid cells. [provided by RefSeq, May 2023]
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Genomic context

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See LOC130056277 in Genome Data Viewer
Location:
chromosome: 14
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (90398461..90398760)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (84623188..84623487)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (90864805..90865104)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene proteasome 26S subunit, ATPase 1 Neighboring gene NRDE-2, necessary for RNA interference, domain containing Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr14:90757747-90758946 Neighboring gene Sharpr-MPRA regulatory region 379 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:90792221-90792722 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:90792723-90793222 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8875 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6006 Neighboring gene ReSE screen-validated silencer GRCh37_chr14:90819601-90819793 Neighboring gene uncharacterized LOC105370618 Neighboring gene ribosomal protein L21 pseudogene 11 Neighboring gene H3K27ac hESC enhancer GRCh37_chr14:90848618-90849145 Neighboring gene H3K27ac hESC enhancer GRCh37_chr14:90849146-90849672 Neighboring gene H3K27ac hESC enhancer GRCh37_chr14:90849673-90850199 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8879 Neighboring gene Sharpr-MPRA regulatory region 5900 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8880 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6008 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6009 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6010 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6011 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr14:90870785-90871984 Neighboring gene calmodulin 1 Neighboring gene MPRA-validated peak2228 silencer Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:90905675-90906438 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8882 Neighboring gene H3K27ac-H3K4me1 hESC enhancers GRCh37_chr14:90920205-90920822 and GRCh37_chr14:90920823-90921440 Neighboring gene long intergenic non-protein coding RNA 2317 Neighboring gene long intergenic non-protein coding RNA 642

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ATAC-STARR-seq reveals transcription factor-bound activators and silencers within chromatin-accessible regions of the human genome. Hansen TJ, et al. Genome Res, 2022 Aug 25. PMID 35858748, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_190698.1 

    Range
    101..400
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

    Range
    90398461..90398760
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060938.1 Alternate T2T-CHM13v2.0

    Range
    84623188..84623487
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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