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LOC130005175 ATAC-STARR-seq lymphoblastoid active region 4321 [ Homo sapiens (human) ]

Gene ID: 130005175, updated on 27-Aug-2024

Summary

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Gene symbol
LOC130005175
Gene description
ATAC-STARR-seq lymphoblastoid active region 4321
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic sequence represents an accessible chromatin region that was validated as an enhancer based on its ability to activate an origin of replication minimal core promoter by the ATAC-STARR-seq (assay for transposase-accessible chromatin with self-transcribing active regulatory region sequencing) massively parallel reporter assay (MPRA) in GM12878 lymphoblastoid cells. [provided by RefSeq, May 2023]
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Genomic context

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Location:
chromosome: 11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (4094559..4095028)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (4159824..4160293)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene stromal interaction molecule 1 Neighboring gene high mobility group nucleosome binding domain 1 pseudogene 21 Neighboring gene ribosomal protein S29 pseudogene 20 Neighboring gene Sharpr-MPRA regulatory region 1570 Neighboring gene Sharpr-MPRA regulatory region 9588 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4320 Neighboring gene ribonucleotide reductase catalytic subunit M1 Neighboring gene olfactory receptor family 55 subfamily B member 1 pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:4199970-4200497 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:4200498-4201024 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3094 Neighboring gene ReSE screen-validated silencer GRCh37_chr11:4210694-4210919 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:4214784-4215284 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:4215285-4215785 Neighboring gene long intergenic non-protein coding RNA 2749

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ATAC-STARR-seq reveals transcription factor-bound activators and silencers within chromatin-accessible regions of the human genome. Hansen TJ, et al. Genome Res, 2022 Aug 25. PMID 35858748, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_184620.1 

    Range
    101..570
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    4094559..4095028
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    4159824..4160293
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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