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LOC129933429 ATAC-STARR-seq lymphoblastoid active region 15537 [ Homo sapiens (human) ]

Gene ID: 129933429, updated on 12-Sep-2024

Summary

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Gene symbol
LOC129933429
Gene description
ATAC-STARR-seq lymphoblastoid active region 15537
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic sequence represents an accessible chromatin region that was validated as an enhancer based on its ability to activate an origin of replication minimal core promoter by the ATAC-STARR-seq (assay for transposase-accessible chromatin with self-transcribing active regulatory region sequencing) massively parallel reporter assay (MPRA) in GM12878 lymphoblastoid cells. [provided by RefSeq, May 2023]
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Genomic context

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See LOC129933429 in Genome Data Viewer
Location:
chromosome: 2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (30293776..30293825)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (30338023..30338072)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (30516642..30516691)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr2:30440807-30442006 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11324 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15533 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15534 Neighboring gene Sharpr-MPRA regulatory region 4877 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:30453066-30453581 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:30453582-30454096 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11327 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11326 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11328 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:30459095-30459302 Neighboring gene H3 histone pseudogene 5 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:30488856-30489470 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:30489471-30490085 Neighboring gene LBH regulator of WNT signaling pathway Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15535 Neighboring gene NANOG hESC enhancer GRCh37_chr2:30511920-30512428 Neighboring gene uncharacterized LOC102723594 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15536 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:30517185-30517355 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:30523745-30524427 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:30525110-30525792 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:30524428-30525109 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:30525793-30526473 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15538 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15539 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15540 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15541 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15542 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15543 Neighboring gene long intergenic non-protein coding RNA 1936 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:30633050-30633962 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15544 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:30666124-30666624 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:30669802-30670539 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:30670540-30671276 Neighboring gene lysocardiolipin acyltransferase 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:30738762-30739262 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:30739263-30739763 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr2:30835819-30836816 Neighboring gene MPRA-validated peak3643 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15548

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ATAC-STARR-seq reveals transcription factor-bound activators and silencers within chromatin-accessible regions of the human genome. Hansen TJ, et al. Genome Res, 2022 Aug 25. PMID 35858748, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_166454.1 

    Range
    101..150
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    30293776..30293825
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    30338023..30338072
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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