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LOC128927529 CapStarr-seq enhancer MGSCv37_chr16:49818780-49819076 [ Mus musculus (house mouse) ]

Gene ID: 128927529, updated on 8-Feb-2024

Summary

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Gene symbol
LOC128927529
Gene description
CapStarr-seq enhancer MGSCv37_chr16:49818780-49819076
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rr370103
Summary
This locus includes a subregion that was identified as a candidate cis-regulatory module (CRM) in developing mouse thymocytes based on a combination of DNase I hypersensitivity and transcription factor binding. That CRM was validated as an active enhancer by high-throughput CapStarr-seq reporter assays showing strong activity in P5424 T cells. This locus also includes a B cell regulatory element that was identified by FAIRE-seq (formaldehyde-assisted isolation of regulatory elements sequencing), and which was validated as an enhancer by STARR-seq (self-transcribing active regulatory region sequencing) in lipopolysaccharide-activated mouse splenic B cells. [provided by RefSeq, Oct 2023]
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Genomic context

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See LOC128927529 in Genome Data Viewer
Location:
chromosome: 16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (49638978..49639326)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene intraflagellar transport 57 Neighboring gene STARR-positive B cell enhancer ABC_E10908 Neighboring gene predicted gene 15518 Neighboring gene STARR-positive B cell enhancer ABC_E9165 Neighboring gene STARR-seq mESC enhancer starr_40971 Neighboring gene predicted gene, 16619 Neighboring gene predicted gene 4633 Neighboring gene STARR-seq mESC enhancer starr_40972 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:49856157-49856266 Neighboring gene CD47 antigen (Rh-related antigen, integrin-associated signal transducer) Neighboring gene STARR-positive B cell enhancer mm9_chr16:49907578-49907878 Neighboring gene STARR-seq mESC enhancer starr_40973 Neighboring gene predicted gene 5486 Neighboring gene predicted gene, 19723

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Other Names

  • STARR-positive B cell enhancer mm9_chr16:49818728-49819029
  • regulatory region 370103

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_153152.2 

    Range
    101..449
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    49638978..49639326
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version