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LOC127886437 H3K27ac hESC enhancer GRCh37_chr17:29335291-29335792 [ Homo sapiens (human) ]

Gene ID: 127886437, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127886437
Gene description
H3K27ac hESC enhancer GRCh37_chr17:29335291-29335792
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac histone modification. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127886437 in Genome Data Viewer
Location:
chromosome: 17
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (31008273..31008774)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (31953994..31954495)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8405 Neighboring gene RNA, 7SL, cytoplasmic 138, pseudogene Neighboring gene ring finger protein 135 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12004 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12005 Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:29297471-29298032 Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:29298033-29298594 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12007 Neighboring gene divergent-paired related homeobox pseudogene 4 Neighboring gene SMAD specific E3 ubiquitin protein ligase 2 (SMURF2) pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8407 Neighboring gene leucine rich repeat containing 37B pseudogene Neighboring gene NF1-REPb PRS3 recombination region Neighboring gene uncharacterized LOC124903974 Neighboring gene MIR4733 host gene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_136155.1 

    Range
    101..602
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

    Range
    31008273..31008774
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    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_025791803.1 Reference GRCh38.p14 PATCHES

    Range
    87447..87948
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060941.1 Alternate T2T-CHM13v2.0

    Range
    31953994..31954495
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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