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LOC127882918 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:3704869-3705396 [ Homo sapiens (human) ]

Gene ID: 127882918, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127882918
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:3704869-3705396
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive and primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127882918 in Genome Data Viewer
Location:
chromosome: 16
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (3654868..3655395)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (3682135..3682662)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (3704869..3705396)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124903632 Neighboring gene NLR family CARD domain containing 3 Neighboring gene uncharacterized LOC105371060 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10327 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10328 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7136 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:3630649-3631444 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10329 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:3639498-3640244 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7137 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10330 Neighboring gene SLX4 structure-specific endonuclease subunit Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10331 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10332 Neighboring gene deoxyribonuclease 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:3690553-3691412 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:3691413-3692270 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:3692271-3693129 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:3694284-3695037 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:3695038-3695790 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:3695791-3696544 Neighboring gene uncharacterized LOC124903631 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:3705397-3705924 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:3721637-3722136 Neighboring gene uncharacterized LOC124903630 Neighboring gene TNF receptor associated protein 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:3746221-3746721 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:3763763-3764271 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7139 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7138 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:3781718-3781878 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:3786759-3787446 Neighboring gene CREB binding protein Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10333 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10334 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10335 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:3872073-3872574 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:3872575-3873074 Neighboring gene DPPA3 pseudogene 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_132884.1 

    Range
    101..628
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    3654868..3655395
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    3682135..3682662
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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