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LOC127829657 OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr15:61656438-61657212 [ Homo sapiens (human) ]

Gene ID: 127829657, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127829657
Gene description
OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr15:61656438-61657212
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer associates with the OCT4 and NANOG transcription factors and is marked by the H3K4me1 histone modification. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127829657 in Genome Data Viewer
Location:
chromosome: 15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (61364239..61365013)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (59167656..59168430)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (61656438..61657212)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene RAR related orphan receptor A Neighboring gene uncharacterized LOC107984805 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6501 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:61438991-61439492 Neighboring gene H3K27ac hESC enhancer GRCh37_chr15:61465732-61466232 Neighboring gene uncharacterized LOC105370841 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr15:61657213-61657987 Neighboring gene uncharacterized LOC105370847 Neighboring gene MPRA-validated peak2363 silencer Neighboring gene uncharacterized LOC107984782 Neighboring gene NANOG hESC enhancer GRCh37_chr15:61829371-61829872 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr15:61848165-61849364 Neighboring gene uncharacterized LOC101928850

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_131139.1 

    Range
    101..875
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    61364239..61365013
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    59167656..59168430
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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