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LOC127826707 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:99188643-99189506 [ Homo sapiens (human) ]

Gene ID: 127826707, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127826707
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:99188643-99189506
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127826707 in Genome Data Viewer
Location:
chromosome: 13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 13 NC_000013.11 (98536389..98537252)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 13 NC_060937.1 (97745088..97745951)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (99188643..99189506)

Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene FERM, ARH/RhoGEF and pleckstrin domain protein 1 Neighboring gene uncharacterized LOC105370327 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7899 Neighboring gene Sharpr-MPRA regulatory region 8978 Neighboring gene FARP1 antisense RNA 1 Neighboring gene Sharpr-MPRA regulatory region 11628 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:99115971-99116472 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr13:99128412-99129611 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7904 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:99133110-99133610 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7905 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:99136594-99137285 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7908 Neighboring gene serine/threonine kinase 24 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:99148205-99149039 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7909 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7910 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7911 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:99159381-99159980 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:99158181-99158780 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:99158781-99159380 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7912 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7913 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:99172581-99173082 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7914 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7915 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7916 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7917 Neighboring gene Sharpr-MPRA regulatory region 8410 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:99220135-99220636 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr13:99222661-99223860 Neighboring gene Sharpr-MPRA regulatory region 9599 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5457 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5458 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5459 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5460 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7919 Neighboring gene STK24 antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7920 Neighboring gene NUS1 pseudogene 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_128212.1 

    Range
    101..964
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000013.11 Reference GRCh38.p14 Primary Assembly

    Range
    98536389..98537252
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060937.1 Alternate T2T-CHM13v2.0

    Range
    97745088..97745951
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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