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LOC127826670 H3K27ac hESC enhancer GRCh37_chr13:95856177-95856677 [ Homo sapiens (human) ]

Gene ID: 127826670, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127826670
Gene description
H3K27ac hESC enhancer GRCh37_chr13:95856177-95856677
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac histone modification. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127826670 in Genome Data Viewer
Location:
chromosome: 13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 13 NC_000013.11 (95203923..95204423)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 13 NC_060937.1 (94408517..94409017)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (95856177..95856677)

Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene VISTA enhancers hs189 and hs341 Neighboring gene long intergenic non-protein coding RNA 557 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr13:95648475-95649263 Neighboring gene RNA, U6 small nuclear 62, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7867 Neighboring gene ATP binding cassette subfamily C member 4 (PEL blood group) Neighboring gene NANOG hESC enhancer GRCh37_chr13:95826697-95827198 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7868 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:95845687-95846187 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr13:95861642-95862841 Neighboring gene Sharpr-MPRA regulatory region 4491 Neighboring gene small nucleolar RNA, C/D box 13G Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7869 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7870 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7871 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7872 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5436 Neighboring gene uncharacterized LOC124903192

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_128175.1 

    Range
    101..601
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000013.11 Reference GRCh38.p14 Primary Assembly

    Range
    95203923..95204423
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060937.1 Alternate T2T-CHM13v2.0

    Range
    94408517..94409017
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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