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LOC127826667 OCT4-NANOG hESC enhancer GRCh37_chr13:95648475-95649263 [ Homo sapiens (human) ]

Gene ID: 127826667, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127826667
Gene description
OCT4-NANOG hESC enhancer GRCh37_chr13:95648475-95649263
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive and primed human embryonic stem cells. This enhancer associates with the OCT4 and NANOG transcription factors. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127826667 in Genome Data Viewer
Location:
chromosome: 13
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 13 NC_000013.11 (94996221..94997009)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 13 NC_060937.1 (94199795..94200583)

Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101927284 Neighboring gene ribosomal protein L21 pseudogene 112 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr13:95600109-95600726 Neighboring gene VISTA enhancers hs189 and hs341 Neighboring gene long intergenic non-protein coding RNA 557 Neighboring gene RNA, U6 small nuclear 62, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7867 Neighboring gene ATP binding cassette subfamily C member 4 (PEL blood group) Neighboring gene NANOG hESC enhancer GRCh37_chr13:95826697-95827198 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7868 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:95845687-95846187 Neighboring gene H3K27ac hESC enhancer GRCh37_chr13:95856177-95856677 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr13:95861642-95862841 Neighboring gene small nucleolar RNA, C/D box 13G

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_128172.1 

    Range
    101..889
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000013.11 Reference GRCh38.p14 Primary Assembly

    Range
    94996221..94997009
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060937.1 Alternate T2T-CHM13v2.0

    Range
    94199795..94200583
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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