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LOC127824713 H3K27ac hESC enhancer GRCh37_chr12:92718856-92719356 [ Homo sapiens (human) ]

Gene ID: 127824713, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127824713
Gene description
H3K27ac hESC enhancer GRCh37_chr12:92718856-92719356
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac histone modification. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127824713 in Genome Data Viewer
Location:
chromosome: 12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (92325080..92325580)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (92302572..92303072)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (92718856..92719356)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 1619 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6721 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6722 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6723 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:92538603-92539139 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6725 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6726 Neighboring gene BTG1 divergent transcript Neighboring gene BTG anti-proliferation factor 1 Neighboring gene ribosomal protein L21 pseudogene 106 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6727 Neighboring gene long intergenic non-protein coding RNA 2391 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6728 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6729 Neighboring gene H3K27ac hESC enhancer GRCh37_chr12:92719357-92719857 Neighboring gene NANOG hESC enhancer GRCh37_chr12:92725117-92725618 Neighboring gene uncharacterized LOC105369902 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6730 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 6731 Neighboring gene CRISPRi-validated cis-regulatory element chr12.2878 Neighboring gene uncharacterized LOC107984467

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_126229.1 

    Range
    101..601
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

    Range
    92325080..92325580
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060936.1 Alternate T2T-CHM13v2.0

    Range
    92302572..92303072
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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