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LOC127819516 H3K4me1 hESC enhancer GRCh37_chr10:126163369-126163869 [ Homo sapiens (human) ]

Gene ID: 127819516, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127819516
Gene description
H3K4me1 hESC enhancer GRCh37_chr10:126163369-126163869
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Nov 2022]
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Genomic context

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See LOC127819516 in Genome Data Viewer
Location:
chromosome: 10
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (124474800..124475300)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (125354237..125354750)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (126163369..126163869)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:126135289-126136156 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr10:126139473-126140028 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr10:126140029-126140585 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2910 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:126152248-126152748 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:126152749-126153249 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:126156959-126157916 Neighboring gene NK1 homeobox 2 Neighboring gene ornithine aminotransferase pseudogene 1 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:126169709-126169860 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:126170100-126170636 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:126172247-126172783 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:126172784-126173319 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:126183769-126184346 Neighboring gene phospholysine phosphohistidine inorganic pyrophosphate phosphatase Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:126184347-126184924 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:126184925-126185502 Neighboring gene ribosomal protein S10 pseudogene 18 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:126210683-126211224 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4166 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_10852 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2911 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:126221662-126222195 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:126222196-126222728 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:126228406-126228906 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4167 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_10867 Neighboring gene Neanderthal introgressed variant-containing enhancers experimental_10870 and experimental_10871 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:126247815-126248795 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:126254941-126255518 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_10873 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:126294466-126295410 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4168 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:126301501-126302011 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4169 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:126310260-126310760 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:126313637-126314592 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:126314593-126315548 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:126315549-126316504 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:126318420-126319272 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:126326782-126327282 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:126328441-126329180 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4170 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:126330659-126331396 Neighboring gene family with sequence similarity 53 member B Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4171 Neighboring gene Sharpr-MPRA regulatory regions 4217 and 14470 Neighboring gene Sharpr-MPRA regulatory region 12473 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4173 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:126347140-126348026 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:126352280-126352937 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:126359217-126359750 Neighboring gene Sharpr-MPRA regulatory region 1593 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:126362023-126362646 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2912 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:126373874-126374845 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:126376343-126376844 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4174 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4175 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:126381504-126381695 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4176 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4177 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4178 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:126388301-126388971 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4179 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:126393799-126394390 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:126397487-126398205 Neighboring gene FAM53B antisense RNA 1 Neighboring gene Sharpr-MPRA regulatory region 10105

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_120987.1 

    Range
    101..601
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    124474800..124475300
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    125354237..125354750
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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