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DNAH14 dynein axonemal heavy chain 14 [ Homo sapiens (human) ]

Gene ID: 127602, updated on 11-Apr-2024

Summary

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Official Symbol
DNAH14provided by HGNC
Official Full Name
dynein axonemal heavy chain 14provided by HGNC
Primary source
HGNC:HGNC:2945
See related
Ensembl:ENSG00000185842 MIM:603341; AllianceGenome:HGNC:2945
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HL18; HL-18; C1orf67; Dnahc14
Summary
Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. Two major classes of dyneins, axonemal and cytoplasmic, have been identified. DNAH14 is an axonemal dynein heavy chain (DHC) (Vaughan et al., 1996 [PubMed 8812413]).[supplied by OMIM, Mar 2008]
Expression
Biased expression in testis (RPKM 2.0), thyroid (RPKM 0.3) and 6 other tissues See more
Orthologs
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Genomic context

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See DNAH14 in Genome Data Viewer
Location:
1q42.12
Exon count:
90
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (224929654..225399286)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (224118326..224587576)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (225117356..225586988)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105373108 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr1:224988386-224988929 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr1:225027656-225028156 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr1:225046922-225048121 Neighboring gene uncharacterized LOC105373109 Neighboring gene uncharacterized LOC124904524 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1854 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:225333859-225334360 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:225334361-225334860 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1855 Neighboring gene MPRA-validated peak726 silencer Neighboring gene MPRA-validated peak727 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2619 Neighboring gene uncharacterized LOC124904525 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_5491 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:225614150-225614822 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:225614823-225615494 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2620 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2621 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2622 Neighboring gene CRISPRi-validated cis-regulatory element chr1.11936 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:225633853-225634413 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:225634414-225634974 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:225634975-225635534 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:225643575-225644075 Neighboring gene Sharpr-MPRA regulatory region 13241 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:225648195-225648876 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:225653249-225654138 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2624 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2625 Neighboring gene long intergenic non-protein coding RNA 2765 Neighboring gene lamin B receptor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. DNAH14 variants are associated with neurodevelopmental disorders. Li J, et al. Hum Mutat, 2022 Jul. PMID 35438214
  2. Clinical and Genetic Spectrum of Children With Primary Ciliary Dyskinesia in China. Guan Y, et al. Chest, 2021 May. PMID 33577779, Free PMC Article
  3. Identification of novel mutations in endometrial cancer patients by whole-exome sequencing. Chang YS, et al. Int J Oncol, 2017 May. PMID 28339086
  4. Identification of embryonic lethal genes in humans by autozygosity mapping and exome sequencing in consanguineous families. Shamseldin HE, et al. Genome Biol, 2015 Jun 3. PMID 26036949, Free PMC Article
  5. Variation in Cilia Protein Genes and Progression of Lung Disease in Cystic Fibrosis. Blue E, et al. Ann Am Thorac Soc, 2018 Apr. PMID 29323929, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Circular RNA DNAH14 molecular mechanism in an experimental model of hepatocellular carcinoma treated with Cobalt chloride to mimic the hypoxia-like response of transcatheter arterial chemoembolization.
    Title: Circular RNA DNAH14 molecular mechanism in an experimental model of hepatocellular carcinoma treated with Cobalt chloride to mimic the hypoxia-like response of transcatheter arterial chemoembolization.
  2. DNAH14 variants are associated with neurodevelopmental disorders.
    Title: DNAH14 variants are associated with neurodevelopmental disorders.
  3. Clinical and Genetic Spectrum of Children With Primary Ciliary Dyskinesia in China.
    Title: Clinical and Genetic Spectrum of Children With Primary Ciliary Dyskinesia in China.
  4. Genetic variants within DNAH6, DNAH14, and DNAAF3 are associated with variation in lung function among persons with cystic fibrosis.
    Title: Variation in Cilia Protein Genes and Progression of Lung Disease in Cystic Fibrosis.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC27277, MGC51214, MGC149665, MGC149666, DKFZp781B1548

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables dynein intermediate chain binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables dynein light intermediate chain binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables minus-end-directed microtubule motor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cilium movement involved in cell motility IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in 9+2 motile cilium IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of dynein complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
dynein axonemal heavy chain 14
Names
axonemal beta dynein heavy chain 14
ciliary dynein heavy chain 14
dynein heavy chain 14, axonemal
dynein, axonemal, heavy polypeptide 14
NP_001138626.1
NP_001336840.1
NP_001336841.1
NP_001354408.1
NP_001354410.1
NP_659426.2
XP_006711798.1
XP_011542360.1
XP_011542361.1
XP_011542363.1
XP_011542364.1
XP_011542365.1
XP_011542366.1
XP_011542367.1
XP_011542368.1
XP_011542369.1
XP_011542371.1
XP_011542372.1
XP_011542373.1
XP_011542374.1
XP_011542375.1
XP_011542376.1
XP_011542378.1
XP_011542383.1
XP_016855784.1
XP_016855785.1
XP_016855786.1
XP_016855787.1
XP_016855788.1
XP_047301580.1
XP_047301627.1
XP_054190324.1
XP_054190325.1
XP_054190326.1
XP_054190327.1
XP_054190328.1
XP_054190329.1
XP_054190330.1
XP_054190331.1
XP_054190332.1
XP_054190333.1
XP_054190334.1
XP_054190335.1
XP_054190336.1
XP_054190337.1
XP_054190338.1
XP_054190339.1
XP_054190340.1
XP_054190341.1
XP_054190342.1
XP_054190343.1
XP_054190344.1
XP_054190345.1
XP_054190346.1
XP_054190347.1
XP_054190348.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_053088.1 RefSeqGene

    Range
    6254..475865
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001145154.3 → NP_001138626.1  dynein axonemal heavy chain 14 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL590547, BC042869, BC119716
    Consensus CDS
    CCDS44322.1
    UniProtKB/Swiss-Prot
    Q0VDD8
    Related
    ENSP00000383737.3, ENST00000400952.7

  2. NM_001349911.2 → NP_001336840.1  dynein axonemal heavy chain 14 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC093560, AL590547
    Consensus CDS
    CCDS86053.1
    UniProtKB/TrEMBL
    M9MMK7
    Related
    ENSP00000355814.1, ENST00000366849.5

  3. NM_001349912.2 → NP_001336841.1  dynein axonemal heavy chain 14 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC093560

  4. NM_001367479.1 → NP_001354408.1  dynein axonemal heavy chain 14 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC092811, AC093560, AL162738, AL357912, AL590547, AL596134, AL645769
    Consensus CDS
    CCDS91163.1
    UniProtKB/TrEMBL
    A0A804HLD3
    Related
    ENSP00000508305.1, ENST00000682510.1

  5. NM_001367481.1 → NP_001354410.1  dynein axonemal heavy chain 14 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC093560

  6. NM_144989.3 → NP_659426.2  dynein axonemal heavy chain 14 isoform 3

    See identical proteins and their annotated locations for NP_659426.2

    Status: VALIDATED

    Source sequence(s)
    AC093560, BC017415, BC119716, CA389321, DB443048
    Consensus CDS
    CCDS41472.1
    UniProtKB/Swiss-Prot
    Q0VDD8
    Related
    ENSP00000355815.3, ENST00000366850.7

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    224929654..225399286
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011544062.3 → XP_011542364.1  dynein axonemal heavy chain 14 isoform X8

    Conserved Domains (5) summary
    pfam03028
    Location:3778 → 4552
    Dynein_heavy; Dynein heavy chain and region D6 of dynein motor
    pfam08393
    Location:992 → 1395
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12777
    Location:3003 → 3337
    MT; Microtubule-binding stalk of dynein motor
    pfam12781
    Location:3363 → 3578
    AAA_9; ATP-binding dynein motor region D5
    cl21455
    Location:1527 → 1754
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  2. XM_011544067.3 → XP_011542369.1  dynein axonemal heavy chain 14 isoform X13

    Conserved Domains (5) summary
    pfam03028
    Location:3778 → 4528
    Dynein_heavy; Dynein heavy chain and region D6 of dynein motor
    pfam08393
    Location:992 → 1395
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12777
    Location:3003 → 3337
    MT; Microtubule-binding stalk of dynein motor
    pfam12781
    Location:3363 → 3578
    AAA_9; ATP-binding dynein motor region D5
    cl21455
    Location:1527 → 1754
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  3. XM_017000296.2 → XP_016855785.1  dynein axonemal heavy chain 14 isoform X5

  4. XM_011544065.3 → XP_011542367.1  dynein axonemal heavy chain 14 isoform X11

    Conserved Domains (5) summary
    pfam03028
    Location:3714 → 4540
    Dynein_heavy; Dynein heavy chain and region D6 of dynein motor
    pfam08393
    Location:992 → 1395
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12777
    Location:2939 → 3273
    MT; Microtubule-binding stalk of dynein motor
    pfam12781
    Location:3299 → 3514
    AAA_9; ATP-binding dynein motor region D5
    cl21455
    Location:1527 → 1754
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  5. XM_011544069.3 → XP_011542371.1  dynein axonemal heavy chain 14 isoform X15

    Conserved Domains (5) summary
    pfam03028
    Location:3660 → 4486
    Dynein_heavy; Dynein heavy chain and region D6 of dynein motor
    pfam08393
    Location:992 → 1395
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12777
    Location:2885 → 3219
    MT; Microtubule-binding stalk of dynein motor
    pfam12781
    Location:3245 → 3460
    AAA_9; ATP-binding dynein motor region D5
    cl21455
    Location:1527 → 1754
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  6. XM_006711735.4 → XP_006711798.1  dynein axonemal heavy chain 14 isoform X4

    Related
    ENSP00000414402.1, ENST00000430092.5
    Conserved Domains (5) summary
    pfam03028
    Location:3747 → 4573
    Dynein_heavy; Dynein heavy chain and region D6 of dynein motor
    pfam08393
    Location:992 → 1395
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12777
    Location:2972 → 3306
    MT; Microtubule-binding stalk of dynein motor
    pfam12781
    Location:3332 → 3547
    AAA_9; ATP-binding dynein motor region D5
    cl21455
    Location:1527 → 1754
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  7. XM_011544064.3 → XP_011542366.1  dynein axonemal heavy chain 14 isoform X10

    Conserved Domains (5) summary
    pfam03028
    Location:3722 → 4548
    Dynein_heavy; Dynein heavy chain and region D6 of dynein motor
    pfam08393
    Location:992 → 1395
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12777
    Location:2947 → 3281
    MT; Microtubule-binding stalk of dynein motor
    pfam12781
    Location:3307 → 3522
    AAA_9; ATP-binding dynein motor region D5
    cl21455
    Location:1527 → 1754
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  8. XM_011544058.3 → XP_011542360.1  dynein axonemal heavy chain 14 isoform X1

    Conserved Domains (5) summary
    pfam03028
    Location:3777 → 4603
    Dynein_heavy; Dynein heavy chain and region D6 of dynein motor
    pfam08393
    Location:992 → 1395
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12777
    Location:3002 → 3336
    MT; Microtubule-binding stalk of dynein motor
    pfam12781
    Location:3362 → 3577
    AAA_9; ATP-binding dynein motor region D5
    cl21455
    Location:1527 → 1754
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  9. XM_011544063.3 → XP_011542365.1  dynein axonemal heavy chain 14 isoform X9

    Conserved Domains (5) summary
    pfam03028
    Location:3725 → 4551
    Dynein_heavy; Dynein heavy chain and region D6 of dynein motor
    pfam08393
    Location:992 → 1395
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12777
    Location:2950 → 3284
    MT; Microtubule-binding stalk of dynein motor
    pfam12781
    Location:3310 → 3525
    AAA_9; ATP-binding dynein motor region D5
    cl21455
    Location:1527 → 1754
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  10. XM_017000297.2 → XP_016855786.1  dynein axonemal heavy chain 14 isoform X7

  11. XM_011544059.3 → XP_011542361.1  dynein axonemal heavy chain 14 isoform X2

    Conserved Domains (5) summary
    pfam03028
    Location:3762 → 4588
    Dynein_heavy; Dynein heavy chain and region D6 of dynein motor
    pfam08393
    Location:992 → 1395
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12777
    Location:2987 → 3321
    MT; Microtubule-binding stalk of dynein motor
    pfam12781
    Location:3347 → 3562
    AAA_9; ATP-binding dynein motor region D5
    cl21455
    Location:1527 → 1754
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  12. XM_011544066.3 → XP_011542368.1  dynein axonemal heavy chain 14 isoform X12

    Conserved Domains (5) summary
    pfam03028
    Location:3706 → 4532
    Dynein_heavy; Dynein heavy chain and region D6 of dynein motor
    pfam08393
    Location:992 → 1395
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12777
    Location:2931 → 3265
    MT; Microtubule-binding stalk of dynein motor
    pfam12781
    Location:3291 → 3506
    AAA_9; ATP-binding dynein motor region D5
    cl21455
    Location:1527 → 1754
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  13. XM_011544061.3 → XP_011542363.1  dynein axonemal heavy chain 14 isoform X6

    Conserved Domains (5) summary
    pfam03028
    Location:3743 → 4569
    Dynein_heavy; Dynein heavy chain and region D6 of dynein motor
    pfam08393
    Location:992 → 1395
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12777
    Location:2968 → 3302
    MT; Microtubule-binding stalk of dynein motor
    pfam12781
    Location:3328 → 3543
    AAA_9; ATP-binding dynein motor region D5
    cl21455
    Location:1527 → 1719
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  14. XM_017000295.2 → XP_016855784.1  dynein axonemal heavy chain 14 isoform X3

  15. XM_011544070.3 → XP_011542372.1  dynein axonemal heavy chain 14 isoform X16

    Conserved Domains (5) summary
    pfam03028
    Location:3652 → 4478
    Dynein_heavy; Dynein heavy chain and region D6 of dynein motor
    pfam08393
    Location:866 → 1269
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12777
    Location:2877 → 3211
    MT; Microtubule-binding stalk of dynein motor
    pfam12781
    Location:3237 → 3452
    AAA_9; ATP-binding dynein motor region D5
    cl21455
    Location:1401 → 1628
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  16. XM_011544072.3 → XP_011542374.1  dynein axonemal heavy chain 14 isoform X18

    Conserved Domains (5) summary
    pfam03028
    Location:3339 → 4165
    Dynein_heavy; Dynein heavy chain and region D6 of dynein motor
    pfam08393
    Location:553 → 956
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12777
    Location:2564 → 2898
    MT; Microtubule-binding stalk of dynein motor
    pfam12781
    Location:2924 → 3139
    AAA_9; ATP-binding dynein motor region D5
    cl21455
    Location:1088 → 1315
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  17. XM_011544071.3 → XP_011542373.1  dynein axonemal heavy chain 14 isoform X17

    Conserved Domains (5) summary
    pfam03028
    Location:3602 → 4428
    Dynein_heavy; Dynein heavy chain and region D6 of dynein motor
    pfam08393
    Location:816 → 1219
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12777
    Location:2827 → 3161
    MT; Microtubule-binding stalk of dynein motor
    pfam12781
    Location:3187 → 3402
    AAA_9; ATP-binding dynein motor region D5
    cl21455
    Location:1351 → 1578
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  18. XM_047445624.1 → XP_047301580.1  dynein axonemal heavy chain 14 isoform X14

  19. XM_017000298.2 → XP_016855787.1  dynein axonemal heavy chain 14 isoform X20

  20. XM_011544073.3 → XP_011542375.1  dynein axonemal heavy chain 14 isoform X19

    Conserved Domains (5) summary
    pfam03028
    Location:3194 → 4020
    Dynein_heavy; Dynein heavy chain and region D6 of dynein motor
    pfam08393
    Location:408 → 811
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12777
    Location:2419 → 2753
    MT; Microtubule-binding stalk of dynein motor
    pfam12781
    Location:2779 → 2994
    AAA_9; ATP-binding dynein motor region D5
    cl21455
    Location:943 → 1170
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  21. XM_011544074.3 → XP_011542376.1  dynein axonemal heavy chain 14 isoform X21

    Conserved Domains (5) summary
    pfam03028
    Location:2984 → 3810
    Dynein_heavy; Dynein heavy chain and region D6 of dynein motor
    pfam08393
    Location:198 → 601
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12777
    Location:2209 → 2543
    MT; Microtubule-binding stalk of dynein motor
    pfam12781
    Location:2569 → 2784
    AAA_9; ATP-binding dynein motor region D5
    cl21455
    Location:733 → 960
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  22. XM_011544076.2 → XP_011542378.1  dynein axonemal heavy chain 14 isoform X22

    Conserved Domains (5) summary
    pfam03028
    Location:2727 → 3553
    Dynein_heavy; Dynein heavy chain and region D6 of dynein motor
    pfam08393
    Location:1 → 344
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12777
    Location:1952 → 2286
    MT; Microtubule-binding stalk of dynein motor
    pfam12781
    Location:2312 → 2527
    AAA_9; ATP-binding dynein motor region D5
    cl21455
    Location:476 → 703
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  23. XM_017000299.2 → XP_016855788.1  dynein axonemal heavy chain 14 isoform X23

  24. XM_011544081.2 → XP_011542383.1  dynein axonemal heavy chain 14 isoform X24

    Conserved Domains (4) summary
    pfam03028
    Location:1964 → 2790
    Dynein_heavy; Dynein heavy chain and region D6 of dynein motor
    pfam12777
    Location:1189 → 1523
    MT; Microtubule-binding stalk of dynein motor
    pfam12781
    Location:1549 → 1764
    AAA_9; ATP-binding dynein motor region D5
    cl21455
    Location:916 → 1177
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  25. XM_047445671.1 → XP_047301627.1  dynein axonemal heavy chain 14 isoform X25

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    224118326..224587576
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054334356.1 → XP_054190331.1  dynein axonemal heavy chain 14 isoform X8

  2. XM_054334361.1 → XP_054190336.1  dynein axonemal heavy chain 14 isoform X13

  3. XM_054334353.1 → XP_054190328.1  dynein axonemal heavy chain 14 isoform X5

  4. XM_054334359.1 → XP_054190334.1  dynein axonemal heavy chain 14 isoform X11

  5. XM_054334363.1 → XP_054190338.1  dynein axonemal heavy chain 14 isoform X15

  6. XM_054334352.1 → XP_054190327.1  dynein axonemal heavy chain 14 isoform X4

  7. XM_054334358.1 → XP_054190333.1  dynein axonemal heavy chain 14 isoform X10

  8. XM_054334349.1 → XP_054190324.1  dynein axonemal heavy chain 14 isoform X1

  9. XM_054334357.1 → XP_054190332.1  dynein axonemal heavy chain 14 isoform X9

  10. XM_054334355.1 → XP_054190330.1  dynein axonemal heavy chain 14 isoform X7

  11. XM_054334350.1 → XP_054190325.1  dynein axonemal heavy chain 14 isoform X2

  12. XM_054334360.1 → XP_054190335.1  dynein axonemal heavy chain 14 isoform X12

  13. XM_054334354.1 → XP_054190329.1  dynein axonemal heavy chain 14 isoform X6

  14. XM_054334351.1 → XP_054190326.1  dynein axonemal heavy chain 14 isoform X3

  15. XM_054334364.1 → XP_054190339.1  dynein axonemal heavy chain 14 isoform X16

  16. XM_054334366.1 → XP_054190341.1  dynein axonemal heavy chain 14 isoform X18

  17. XM_054334365.1 → XP_054190340.1  dynein axonemal heavy chain 14 isoform X17

  18. XM_054334362.1 → XP_054190337.1  dynein axonemal heavy chain 14 isoform X14

  19. XM_054334368.1 → XP_054190343.1  dynein axonemal heavy chain 14 isoform X20

  20. XM_054334367.1 → XP_054190342.1  dynein axonemal heavy chain 14 isoform X19

  21. XM_054334369.1 → XP_054190344.1  dynein axonemal heavy chain 14 isoform X21

  22. XM_054334370.1 → XP_054190345.1  dynein axonemal heavy chain 14 isoform X22

  23. XM_054334371.1 → XP_054190346.1  dynein axonemal heavy chain 14 isoform X23

  24. XM_054334372.1 → XP_054190347.1  dynein axonemal heavy chain 14 isoform X24

  25. XM_054334373.1 → XP_054190348.1  dynein axonemal heavy chain 14 isoform X25

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001373.1: Suppressed sequence

    Description
    NM_001373.1: This RefSeq was removed because there is insufficient support for the transcript and protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q0VDD8.3 GenPept UniProtKB/Swiss-Prot:Q0VDD8

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