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LOC127459701 H3K4me1 hESC enhancer GRCh37_chr8:68644182-68644682 [ Homo sapiens (human) ]

Gene ID: 127459701, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127459701
Gene description
H3K4me1 hESC enhancer GRCh37_chr8:68644182-68644682
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127459701 in Genome Data Viewer
Location:
chromosome: 8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (67731947..67732447)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (68158371..68158871)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (68644182..68644682)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene carboxypeptidase A6 Neighboring gene uncharacterized LOC105375886 Neighboring gene MT-ND4L pseudogene 27 Neighboring gene MT-ATP6 pseudogene 12 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:68552088-68552901 Neighboring gene MT-CO3 pseudogene 3 Neighboring gene Sharpr-MPRA regulatory region 5318 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:68631627-68632132 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:68632133-68632636 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr8:68632637-68633142 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr8:68633143-68633647 Neighboring gene Sharpr-MPRA regulatory region 913 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:68658421-68658921 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr8:68766696-68767468 Neighboring gene NANOG hESC enhancer GRCh37_chr8:68796257-68797054 Neighboring gene NADH:ubiquinone oxidoreductase subunit S5 pseudogene 6 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr8:68867393-68868063 Neighboring gene NANOG hESC enhancer GRCh37_chr8:68882966-68883467 Neighboring gene phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 Neighboring gene MPRA-validated peak7060 silencer Neighboring gene uncharacterized LOC105375888

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_114470.1 

    Range
    101..601
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    67731947..67732447
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    68158371..68158871
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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