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LOC127458349 H3K4me1 hESC enhancer GRCh37_chr7:158330775-158331759 [ Homo sapiens (human) ]

Gene ID: 127458349, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127458349
Gene description
H3K4me1 hESC enhancer GRCh37_chr7:158330775-158331759
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127458349 in Genome Data Viewer
Location:
chromosome: 7
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (158538083..158539067)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (159747444..159748428)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene protein tyrosine phosphatase receptor type N2 Neighboring gene uncharacterized LOC105375613 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:157783213-157783812 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:157783813-157784412 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:157782013-157782612 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:157791993-157792738 Neighboring gene NANOG hESC enhancer GRCh37_chr7:157792768-157793272 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:157799559-157800539 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:157800540-157801519 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:157802753-157803315 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:157808367-157809026 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:157809027-157809686 Neighboring gene Sharpr-MPRA regulatory region 9999 Neighboring gene ReSE screen-validated silencer GRCh37_chr7:157843588-157843764 Neighboring gene MPRA-validated peak6878 silencer Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:157859561-157860514 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:157870087-157870586 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:157904657-157905158 Neighboring gene Sharpr-MPRA regulatory region 5343 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:157903511-157904242 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:157926052-157926594 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:157929890-157930772 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:157935377-157936298 Neighboring gene OCT4-H3K27ac hESC enhancer GRCh37_chr7:157940629-157941180 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:157941181-157941730 Neighboring gene D7S22 minisatellite repeat instability region Neighboring gene ReSE screen-validated silencer GRCh37_chr7:157954594-157954842 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:157957089-157957613 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:157987247-157987747 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:158030483-158031396 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:158037992-158038492 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:158053060-158053970 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:158069190-158069934 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:158073864-158074606 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:158075350-158076092 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:158103424-158103936 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:158109662-158110412 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:158108910-158109661 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:158110413-158111164 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:158118125-158119111 Neighboring gene ReSE screen-validated silencer GRCh37_chr7:158122041-158122238 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:158127303-158127803 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:158134077-158134576 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr7:158134599-158135798 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:158142965-158143559 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:158144749-158145341 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr7:158166900-158168099 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:158190023-158190630 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:158206830-158207354 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:158207355-158207879 Neighboring gene MPRA-validated peak6880 silencer Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr7:158230280-158230780 Neighboring gene ReSE screen-validated silencer GRCh37_chr7:158261913-158262077 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_98034 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:158289893-158290448 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:158292995-158293940 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:158300949-158301460 Neighboring gene Sharpr-MPRA regulatory region 11620 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:158319662-158320162 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:158320163-158320663 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:158322953-158323722 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:158323723-158324491 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:158342742-158343550 Neighboring gene MPRA-validated peak6883 silencer Neighboring gene uncharacterized LOC124901793 Neighboring gene Sharpr-MPRA regulatory region 10119 Neighboring gene long intergenic non-protein coding RNA 1022 Neighboring gene microRNA 595 Neighboring gene microRNA 5707

Genomic regions, transcripts, and products

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Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_113122.1 

    Range
    101..1085
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    158538083..158539067
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    159747444..159748428
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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