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LOC127408623 NANOG-H3K27ac hESC enhancer GRCh37_chr7:23028535-23029046 [ Homo sapiens (human) ]

Gene ID: 127408623, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127408623
Gene description
NANOG-H3K27ac hESC enhancer GRCh37_chr7:23028535-23029046
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer associates with the NANOG transcription factor and is marked by the H3K27ac histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127408623 in Genome Data Viewer
Location:
chromosome: 7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (22988916..22989427)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (23125492..23125988)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (23028535..23029046)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107986776 Neighboring gene uncharacterized LOC124901600 Neighboring gene ribosomal protein L12 pseudogene 10 Neighboring gene hyccin PI4KA lipid kinase complex subunit 1 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr7:23029047-23029557 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25713 Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:23052451-23053132 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18005 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25714 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25715 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr7:23060419-23061618 Neighboring gene uncharacterized LOC105375185 Neighboring gene uncharacterized LOC105375186

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_110591.1 

    Range
    101..612
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    22988916..22989427
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    23125492..23125988
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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