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LOC127401921 OCT4-NANOG hESC enhancer GRCh37_chr4:173630272-173631010 [ Homo sapiens (human) ]

Gene ID: 127401921, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127401921
Gene description
OCT4-NANOG hESC enhancer GRCh37_chr4:173630272-173631010
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer associates with the OCT4 and NANOG transcription factors. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127401921 in Genome Data Viewer
Location:
chromosome: 4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (172709121..172709859)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (176048580..176049318)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (173630272..173631010)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene polypeptide N-acetylgalactosaminyltransferase like 6 Neighboring gene uncharacterized LOC124900811 Neighboring gene ubiquitin conjugating enzyme E2 N pseudogene Neighboring gene GALNTL6 antisense RNA 1 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr4:173730432-173730959 Neighboring gene uncharacterized LOC107986201 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:173896580-173897080 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22153 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:173991635-173992284 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:173994926-173995724 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:173995725-173996523 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:174004943-174005676 Neighboring gene GALNT7 divergent transcript Neighboring gene RNA, 7SL, cytoplasmic 253, pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_103880.1 

    Range
    101..839
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

    Range
    172709121..172709859
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060928.1 Alternate T2T-CHM13v2.0

    Range
    176048580..176049318
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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