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LOC127398989 NANOG hESC enhancer GRCh37_chr3:151978898-151979587 [ Homo sapiens (human) ]

Gene ID: 127398989, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127398989
Gene description
NANOG hESC enhancer GRCh37_chr3:151978898-151979587
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer associates with the NANOG transcription factor. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127398989 in Genome Data Viewer
Location:
chromosome: 3
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (152261109..152261798)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (155029008..155029697)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107986047 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20702 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20703 Neighboring gene long intergenic non-protein coding RNA 2917 Neighboring gene uncharacterized LOC101928166 Neighboring gene Sharpr-MPRA regulatory region 12239 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20704 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20705 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:151985921-151986763 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:151986764-151987605 Neighboring gene MBNL1 antisense RNA 1 Neighboring gene muscleblind like splicing regulator 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20707 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20708 Neighboring gene transmembrane protein 14E, pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_100955.1 

    Range
    101..790
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    152261109..152261798
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    155029008..155029697
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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