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LOC127396879 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:17535720-17536296 [ Homo sapiens (human) ]

Gene ID: 127396879, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127396879
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:17535720-17536296
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127396879 in Genome Data Viewer
Location:
chromosome: 3
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (17494228..17494804)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (17496412..17496988)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene TBC1 domain family member 5 Neighboring gene RBIS pseudogene 6 Neighboring gene MPRA-validated peak4551 silencer Neighboring gene Sharpr-MPRA regulatory region 9690 Neighboring gene ribosomal protein L31 pseudogene 19 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr3:17588257-17589120 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19571 Neighboring gene MPRA-validated peak4555 silencer Neighboring gene MPRA-validated peak4556 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:17734513-17735014 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:17735015-17735514 Neighboring gene RNA, U7 small nuclear 10 pseudogene Neighboring gene tRNA-Cys (anticodon GCA) 25-1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_098849.1 

    Range
    101..677
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    17494228..17494804
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    17496412..17496988
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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