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LOC127275705 H3K27ac hESC enhancer GRCh37_chr2:216877329-216878096 [ Homo sapiens (human) ]

Gene ID: 127275705, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127275705
Gene description
H3K27ac hESC enhancer GRCh37_chr2:216877329-216878096
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac histone modification. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127275705 in Genome Data Viewer
Location:
chromosome: 2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (216012606..216013373)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (216498037..216498804)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (216877329..216878096)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 607 Neighboring gene cytochrome c oxidase subunit NDUFA4-like Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17074 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17075 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17076 Neighboring gene uncharacterized LOC105373870 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:216786644-216787283 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:216787284-216787924 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr2:216792334-216792860 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12301 Neighboring gene melanoregulin Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17077 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17078 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17080 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17079 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17081 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12302 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17082 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17083 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17084 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17085 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17086 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17087 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12303 Neighboring gene peroxisomal trans-2-enoyl-CoA reductase Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17088 Neighboring gene transmembrane protein 169

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_097553.1 

    Range
    101..868
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    216012606..216013373
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    216498037..216498804
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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