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LOC127273436 H3K4me1 hESC enhancer GRCh37_chr2:60721043-60721542 [ Homo sapiens (human) ]

Gene ID: 127273436, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127273436
Gene description
H3K4me1 hESC enhancer GRCh37_chr2:60721043-60721542
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Oct 2022]
Annotation information
Note: This locus has been reviewed for its involvement in coronavirus biology, and is regulatory element in the vicinity of coronavirus related gene(s).
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Genomic context

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See LOC127273436 in Genome Data Viewer
Location:
chromosome: 2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (60493908..60494407)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (60499822..60500321)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (60721043..60721542)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102724142 Neighboring gene uncharacterized LOC124906010 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15803 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11509 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15804 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15805 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15806 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15807 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15808 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:60680131-60681128 Neighboring gene BCL11 transcription factor A Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr2:60703617-60704430 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:60708187-60708687 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:60711909-60712410 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:60712411-60712910 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:60720541-60721042 Neighboring gene NANOG hESC enhancer GRCh37_chr2:60724096-60724705 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11510 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15809 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15810 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15811 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15812 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11511 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:60758966-60759525 Neighboring gene VISTA enhancer hs957 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:60776677-60777449 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:60777450-60778222 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11513 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11514 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11515 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11516 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15814 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11517 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr2:60782673-60783281 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15815 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11518 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:60809095-60809244 Neighboring gene VISTA enhancer hs1142 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr2:60860521-60861233 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11519 Neighboring gene RNA, 7SL, cytoplasmic 361, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15816 Neighboring gene IFITM3 pseudogene 9

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_095287.1 

    Range
    101..600
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    60493908..60494407
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    60499822..60500321
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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