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LOC127267478 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:11539763-11540364 [ Homo sapiens (human) ]

Gene ID: 127267478, updated on 10-Oct-2023

Summary

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Gene symbol
LOC127267478
Gene description
H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:11539763-11540364
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Oct 2022]
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Genomic context

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See LOC127267478 in Genome Data Viewer
Location:
chromosome: 1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (11479706..11480307)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (11022648..11023249)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124903841 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:11455587-11456086 Neighboring gene MPRA-validated peak75 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:11476310-11476994 Neighboring gene MT-CYB pseudogene 45 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 264 Neighboring gene uncharacterized LOC124903842 Neighboring gene dispatched RND transporter family member 3 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:11561504-11562071 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:11575295-11575922 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:11619527-11620028 Neighboring gene Sharpr-MPRA regulatory region 3841 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:11640244-11640440 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:11660896-11661396 Neighboring gene long intergenic non-protein coding RNA 1647

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_089353.1 

    Range
    101..702
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    11479706..11480307
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    11022648..11023249
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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