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T7p17 Gp2.5-like ssDNA binding protein and ssDNA annealing protein [ Escherichia phage T7 ]

Gene ID: 1261080, updated on 18-Aug-2023

Summary

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Gene symbol
T7p17
Gene description
Gp2.5-like ssDNA binding protein and ssDNA annealing protein
Locus tag
T7p17
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia phage T7 (nat-host: Escherichia coli)
Lineage
Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Autographiviridae; Studiervirinae; Teseptimavirus
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Genomic context

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Sequence:
NC_001604.1 (9158..9856)

NC_001604.1Genomic Context describing neighboring genes Neighboring gene nucleotide kinase Neighboring gene hypothetical protein Neighboring gene RNA polymerase inhibitor Neighboring gene endonuclease Neighboring gene endonuclease Neighboring gene amidase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001604.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Kinetics and thermodynamics of salt-dependent T7 gene 2.5 protein binding to single- and double-stranded DNA. Shokri L, et al. Nucleic Acids Res, 2008 Oct. PMID 18772224, Free PMC Article
  2. Two modes of interaction of the single-stranded DNA-binding protein of bacteriophage T7 with the DNA polymerase-thioredoxin complex. Ghosh S, et al. J Biol Chem, 2010 Jun 4. PMID 20375019, Free PMC Article
  3. Gene 5.5 protein of bacteriophage T7 inhibits the nucleoid protein H-NS of Escherichia coli. Liu Q, et al. Proc Natl Acad Sci U S A, 1993 Mar 1. PMID 7680479, Free PMC Article
  4. Complete nucleotide sequence of bacteriophage T7 DNA and the locations of T7 genetic elements. Dunn JJ, et al. J Mol Biol, 1983 Jun 5. PMID 6864790
  5. Bacteriophage T7 E promoter: identification and measurement of kinetics of association with Escherichia coli RNA polymerase. Prosen DE, et al. Biochemistry, 1985 Apr 23. PMID 3922411

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Regulation of T7 gp2.5 binding dynamics by its C-terminal tail, template conformation and sequence.
    Title: Regulation of T7 gp2.5 binding dynamics by its C-terminal tail, template conformation and sequence.
  2. analysis of the interaction of the single-stranded DNA-binding protein of bacteriophage T7 with the DNA polymerase-thioredoxin complex
    Title: Two modes of interaction of the single-stranded DNA-binding protein of bacteriophage T7 with the DNA polymerase-thioredoxin complex.
  3. results support a model in which dimerization interactions must be broken for DNA binding, and gp2.5 monomers search dsDNA by 1D diffusion to bind ssDNA.
    Title: Kinetics and thermodynamics of salt-dependent T7 gene 2.5 protein binding to single- and double-stranded DNA.
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General gene information

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Homology

  • gene 2.5

General protein information

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Preferred Names
Gp2.5-like ssDNA binding protein and ssDNA annealing protein
NP_041970.1
  • binds single-stranded DNA. In phage T7 gp2.5 is essential for DNA replication and recombination. Other names: gp2.5; SSB.

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001604.1 Reference assembly

    Range
    9158..9856
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_041970.1 Gp2.5-like ssDNA binding protein and ssDNA annealing protein [Escherichia phage T7]

    See identical proteins and their annotated locations for NP_041970.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P03696
    UniProtKB/TrEMBL
    A0A2P0ZKN3, Q6WYF1, Q6WYQ7
    Conserved Domains (1) summary
    PHA00458
    Location:1 → 211
    PHA00458; single-stranded DNA-binding protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P03696.1

Gene LinkOut

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Research Materials