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folE GTP cyclohydrolase I [ Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 ]

Gene ID: 1253715, updated on 6-Oct-2023

Summary

Gene symbol
folE
Gene description
GTP cyclohydrolase I
Locus tag
STM2193
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 (strain: LT2, serovar: Typhimurium, sub-species: enterica, culture-collection: ATCC:700720, culture-collection: SGSC:1412, type-material: type strain of Salmonella enterica)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Salmonella
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Genomic context

Sequence:
NC_003197.2 (2290442..2291126, complement)

NC_003197.2Genomic Context describing neighboring genes Neighboring gene GalR/LacI family transcriptional repressor of mgl operon Neighboring gene putative inner membrane protein Neighboring gene putative esterase Neighboring gene putative transcriptional regulator Neighboring gene putative D-serine dehydratase

General gene information

regulatory

  • Loc: c2291126-2291121 regulatory_class = ribosome_binding_site

General protein information

Preferred Names
GTP cyclohydrolase I
NP_461138.1
  • similar to E. coli GTP cyclohydrolase I (AAC75214.1); Blastp hit to AAC75214.1 (222 aa), 96% identity in aa 1 - 221

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003197.2 Reference assembly

    Range
    2290442..2291126 complement
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    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_461138.1 GTP cyclohydrolase I [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]

    See identical proteins and their annotated locations for NP_461138.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A379US70, A0A3U2RZ77, A0A4Z0LEY8, A0A5U4C3G8, A0A5W1UA30, A0A620XX00, A0A629J3W2, A0A659Q6I4, A0A6Y0U8R4, A0A6Y5G8Q0, A0A725Q176, A0A749KSS9
    Conserved Domains (1) summary
    cl00263
    Location:40220
    TFold; Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1), 6-pyrovoyl ...